Detailed information NTG0978508

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS37642_RS07530
• Genome accession: NZ_CP151468
• Coordinates: 1458114..1458839 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS37642
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1453114..1463839

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS37642_RS07495 (MGAS37642_03074)	-	1453248..1453631 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
MGAS37642_RS07500 (MGAS37642_03076)	-	1453642..1454193 (+)	552	WP_002988670.1	hypothetical protein	-
MGAS37642_RS07505 (MGAS37642_03078)	-	1454310..1455389 (+)	1080	WP_002988667.1	site-specific integrase	-
MGAS37642_RS07515 (MGAS37642_03082)	trmB	1455587..1456222 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS37642_RS07520 (MGAS37642_03084)	ccrZ	1456222..1457013 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS37642_RS07525 (MGAS37642_03086)	-	1457077..1458111 (-)	1035	WP_010922583.1	ABC transporter permease	-
MGAS37642_RS07530 (MGAS37642_03088)	pptA	1458114..1458839 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS37642_RS07535 (MGAS37642_03090)	-	1458911..1459330 (+)	420	WP_002983376.1	HIT family protein	-
MGAS37642_RS07540 (MGAS37642_03092)	-	1459327..1459683 (+)	357	WP_002988657.1	hypothetical protein	-
MGAS37642_RS07545 (MGAS37642_03094)	brpA	1459794..1461068 (-)	1275	WP_010922584.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS37642_RS07550 (MGAS37642_03096)	-	1461077..1461601 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
MGAS37642_RS07555 (MGAS37642_03098)	tsaE	1461576..1462037 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS37642_RS07560 (MGAS37642_03100)	-	1462191..1463651 (-)	1461	WP_011285677.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=978508 MGAS37642_RS07530 WP_002983379.1 1458114..1458839(-) (pptA) [Streptococcus pyogenes strain MGAS37642]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=978508 MGAS37642_RS07530 WP_002983379.1 1458114..1458839(-) (pptA) [Streptococcus pyogenes strain MGAS37642]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714