Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8619_RS09730 Genome accession   NZ_AP026918
Coordinates   1872402..1873355 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain PZ900700009     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1867402..1878355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8619_RS09700 (PC0009_18780) - 1868163..1868786 (-) 624 WP_000932657.1 hypothetical protein -
  R8619_RS09705 (PC0009_18790) jag 1868837..1869823 (-) 987 WP_000260027.1 RNA-binding cell elongation regulator Jag/EloR -
  R8619_RS09710 (PC0009_18800) - 1869842..1870666 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  R8619_RS09715 (PC0009_18810) rnpA 1870641..1871012 (-) 372 WP_000739244.1 ribonuclease P protein component -
  R8619_RS09720 - 1871029..1871160 (-) 132 WP_000768904.1 hypothetical protein -
  R8619_RS09725 (PC0009_18820) - 1871161..1872351 (-) 1191 WP_000167752.1 acetate kinase -
  R8619_RS09730 (PC0009_18830) comYH 1872402..1873355 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  R8619_RS09735 - 1873416..1874010 (-) 595 Protein_1890 class I SAM-dependent methyltransferase -
  R8619_RS09740 (PC0009_18860) comGG/cglG 1874147..1874560 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8619_RS09745 (PC0009_18870) comGF/cglF 1874538..1874999 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8619_RS09750 (PC0009_18880) comGE/cglE 1874962..1875264 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8619_RS09755 (PC0009_18890) comGD/cglD 1875227..1875631 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8619_RS09760 (PC0009_18900) comGC/cglC 1875624..1875950 (-) 327 WP_050260822.1 comG operon protein ComGC Machinery gene
  R8619_RS09765 (PC0009_18910) comGB/cglB 1875952..1876968 (-) 1017 WP_073177425.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8619_RS09770 (PC0009_18920) comGA/cglA/cilD 1876916..1877857 (-) 942 WP_000249559.1 competence type IV pilus ATPase ComGA Machinery gene
  R8619_RS09775 (PC0009_18930) - 1877933..1878298 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=97826 R8619_RS09730 WP_000345126.1 1872402..1873355(-) (comYH) [Streptococcus pneumoniae strain PZ900700009]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=97826 R8619_RS09730 WP_000345126.1 1872402..1873355(-) (comYH) [Streptococcus pneumoniae strain PZ900700009]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment