Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACM6AQ_RS07980 Genome accession   NZ_CP181136
Coordinates   1654860..1656122 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain AG21-0619     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1649860..1661122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AQ_RS07955 (ACM6AQ_07955) - 1650058..1650726 (-) 669 WP_000805942.1 uroporphyrinogen-III synthase -
  ACM6AQ_RS07960 (ACM6AQ_07960) hemC 1650748..1651674 (-) 927 WP_001230228.1 hydroxymethylbilane synthase -
  ACM6AQ_RS07965 (ACM6AQ_07965) ccsA 1651716..1652531 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACM6AQ_RS07970 (ACM6AQ_07970) hemA 1652553..1653899 (-) 1347 WP_000545460.1 glutamyl-tRNA reductase -
  ACM6AQ_RS07975 (ACM6AQ_07975) yihA 1654116..1654706 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACM6AQ_RS07980 (ACM6AQ_07980) clpX 1654860..1656122 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACM6AQ_RS07985 (ACM6AQ_07985) tig 1656273..1657574 (-) 1302 WP_072491707.1 trigger factor -
  ACM6AQ_RS07990 (ACM6AQ_07990) - 1657622..1657732 (-) 111 WP_072491706.1 hypothetical protein -
  ACM6AQ_RS07995 (ACM6AQ_07995) - 1657737..1658666 (-) 930 WP_001280020.1 hypothetical protein -
  ACM6AQ_RS08000 (ACM6AQ_08000) - 1658685..1659293 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  ACM6AQ_RS08005 (ACM6AQ_08005) rplT 1659435..1659791 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  ACM6AQ_RS08010 (ACM6AQ_08010) rpmI 1659838..1660038 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  ACM6AQ_RS08015 (ACM6AQ_08015) infC 1660067..1660594 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=978092 ACM6AQ_RS07980 WP_000472293.1 1654860..1656122(-) (clpX) [Staphylococcus aureus strain AG21-0619]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=978092 ACM6AQ_RS07980 WP_000472293.1 1654860..1656122(-) (clpX) [Staphylococcus aureus strain AG21-0619]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTTGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCCCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCCATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment