Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R8619_RS07170 Genome accession   NZ_AP026918
Coordinates   1406772..1408004 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain PZ900700009     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1401772..1413004
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8619_RS07140 (PC0009_14110) - 1401959..1402927 (+) 969 WP_000081004.1 NAD(P)/FAD-dependent oxidoreductase -
  R8619_RS07145 (PC0009_14120) whiA 1402961..1403872 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  R8619_RS07150 (PC0009_14130) - 1403869..1404846 (-) 978 WP_001231086.1 YvcK family protein -
  R8619_RS07155 (PC0009_14140) rapZ 1404843..1405733 (-) 891 WP_000163033.1 RNase adapter RapZ -
  R8619_RS07160 (PC0009_14150) - 1405785..1406165 (-) 381 WP_001140412.1 RidA family protein -
  R8619_RS07165 (PC0009_14160) yihA 1406176..1406763 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R8619_RS07170 (PC0009_14170) clpX 1406772..1408004 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R8619_RS07175 - 1408036..1408206 (-) 171 WP_000442275.1 hypothetical protein -
  R8619_RS07180 (PC0009_14180) - 1408206..1408712 (-) 507 WP_000162484.1 dihydrofolate reductase -
  R8619_RS07185 (PC0009_14190) - 1408842..1409360 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  R8619_RS07190 (PC0009_14200) - 1409934..1411190 (+) 1257 WP_000436627.1 ISL3 family transposase -
  R8619_RS07195 (PC0009_14210) lytC 1411279..1412784 (-) 1506 WP_075575672.1 choline binding-anchored murein hydrolase LytC -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=97801 R8619_RS07170 WP_000106346.1 1406772..1408004(-) (clpX) [Streptococcus pneumoniae strain PZ900700009]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=97801 R8619_RS07170 WP_000106346.1 1406772..1408004(-) (clpX) [Streptococcus pneumoniae strain PZ900700009]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment