Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8619_RS01850 Genome accession   NZ_AP026918
Coordinates   352198..352887 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain PZ900700009     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 347198..357887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8619_RS01825 (PC0009_03520) gpsB 347331..347660 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8619_RS01835 (PC0009_03530) - 348146..349303 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  R8619_RS01840 (PC0009_03540) mapZ 349316..350686 (+) 1371 WP_000039285.1 mid-cell-anchored protein MapZ -
  R8619_RS01845 (PC0009_03550) gndA 350762..352186 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R8619_RS01850 (PC0009_03560) covR 352198..352887 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  R8619_RS01855 (PC0009_03570) cbpC 352985..354004 (+) 1020 WP_000771097.1 choline-binding protein CbpC -
  R8619_RS01860 (PC0009_03580) - 354122..355354 (-) 1233 WP_000765693.1 MFS transporter -
  R8619_RS01865 (PC0009_03590) - 355365..355817 (-) 453 WP_000499615.1 lanthionine synthetase -
  R8619_RS01870 (PC0009_03600) - 355885..356273 (-) 389 Protein_364 lanthionine synthetase LanC family protein -
  R8619_RS10870 - 356885..357052 (+) 168 Protein_365 transposase -
  R8619_RS10875 - 357092..357214 (+) 123 Protein_366 cell wall-binding protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=97778 R8619_RS01850 WP_000518008.1 352198..352887(+) (covR) [Streptococcus pneumoniae strain PZ900700009]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=97778 R8619_RS01850 WP_000518008.1 352198..352887(+) (covR) [Streptococcus pneumoniae strain PZ900700009]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAACTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment