Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   R8619_RS00110 Genome accession   NZ_AP026918
Coordinates   21282..21518 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700009     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 20765..20965 21282..21518 flank 317


Gene organization within MGE regions


Location: 20765..21518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8619_RS00110 (PC0009_00160) comW 21282..21518 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=97770 R8619_RS00110 WP_000939545.1 21282..21518(+) (comW) [Streptococcus pneumoniae strain PZ900700009]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=97770 R8619_RS00110 WP_000939545.1 21282..21518(+) (comW) [Streptococcus pneumoniae strain PZ900700009]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTAAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1

  comW Streptococcus pneumoniae D39

100

100

1

  comW Streptococcus pneumoniae R6

100

100

1

  comW Streptococcus pneumoniae TIGR4

100

100

1

  comW Streptococcus mitis SK321

75.641

100

0.756

  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744


Multiple sequence alignment