Detailed information NTG0097733

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8563_RS08840
• Genome accession: NZ_AP026917
• Coordinates: 1714752..1715819 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain PZ900700007
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1709752..1720819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8563_RS08810 (PC0007_17310)	treR	1709924..1710634 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
R8563_RS08815 (PC0007_17320)	-	1710667..1711470 (-)	804	WP_000202630.1	ABC transporter ATP-binding protein	-
R8563_RS08820 (PC0007_17330)	-	1711483..1712376 (-)	894	WP_001012092.1	ABC transporter permease	-
R8563_RS08825 (PC0007_17340)	-	1712388..1713197 (-)	810	WP_001850051.1	ABC transporter substrate-binding protein	-
R8563_RS08830	-	1713618..1713749 (-)	132	WP_000787593.1	hypothetical protein	-
R8563_RS08835 (PC0007_17350)	amiF	1713815..1714741 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R8563_RS08840 (PC0007_17360)	amiE	1714752..1715819 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
R8563_RS08845 (PC0007_17370)	amiD	1715828..1716754 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8563_RS08850 (PC0007_17380)	amiC	1716754..1718250 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
R8563_RS08855 (PC0007_17390)	amiA3	1718317..1720296 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=97733 R8563_RS08840 WP_000159554.1 1714752..1715819(-) (amiE) [Streptococcus pneumoniae strain PZ900700007]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=97733 R8563_RS08840 WP_000159554.1 1714752..1715819(-) (amiE) [Streptococcus pneumoniae strain PZ900700007]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541