Detailed information NTG0097727

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ACAM23_RS09685
• Genome accession: NZ_AP031394
• Coordinates: 1858044..1858943 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904865.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P28
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1853044..1863943

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM23_RS09660 (SPNE16P28_18870)	rsmA	1853380..1854252 (-)	873	WP_219599541.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
ACAM23_RS09665 (SPNE16P28_18880)	-	1854383..1854691 (-)	309	WP_000333257.1	hypothetical protein	-
ACAM23_RS09670 (SPNE16P28_18890)	-	1854684..1855325 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
ACAM23_RS09675 (SPNE16P28_18900)	-	1855327..1857357 (-)	2031	WP_369608092.1	bacteriocin-associated integral membrane family protein	-
ACAM23_RS09680 (SPNE16P28_18910)	-	1857434..1857730 (-)	297	WP_000815393.1	lactococcin 972 family bacteriocin	-
ACAM23_RS09685 (SPNE16P28_18920)	comR	1858044..1858943 (-)	900	WP_000904865.1	helix-turn-helix domain-containing protein	Regulator
ACAM23_RS09690 (SPNE16P28_18930)	rnmV	1859015..1859575 (-)	561	WP_000664448.1	ribonuclease M5	-
ACAM23_RS09695 (SPNE16P28_18940)	-	1859575..1860348 (-)	774	WP_000575635.1	TatD family hydrolase	-
ACAM23_RS09700 (SPNE16P28_18950)	-	1860653..1861630 (-)	978	Protein_1899	DUF1542 domain-containing protein	-
ACAM23_RS09705 (SPNE16P28_18960)	rpmH	1861836..1861970 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
ACAM23_RS09710 (SPNE16P28_18970)	-	1862115..1863329 (-)	1215	WP_000666465.1	pyridoxal phosphate-dependent aminotransferase	-
ACAM23_RS09715 (SPNE16P28_18980)	-	1863485..1863778 (-)	294	WP_000977364.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35175.08 Da
• Isoelectric Point: 5.2018

>NTDB_id=97727 ACAM23_RS09685 WP_000904865.1 1858044..1858943(-) (comR) [Streptococcus pneumoniae strain 16P28]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=97727 ACAM23_RS09685 WP_000904865.1 1858044..1858943(-) (comR) [Streptococcus pneumoniae strain 16P28]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

• Helix-turn-helix (HTH_3) (7-59)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.095	98.328	0.375
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368