Detailed information NTG0976909

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: MGAS38289_RS00620
• Genome accession: NZ_CP151440
• Coordinates: 98948..99382 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS38289
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 93948..104382

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS38289_RS00590 (MGAS38289_00240)	-	95617..95982 (+)	366	WP_002986560.1	DUF1033 family protein	-
MGAS38289_RS00595 (MGAS38289_00242)	comYA	96075..97013 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
MGAS38289_RS00600 (MGAS38289_00244)	comYB	96949..97983 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGAS38289_RS00605 (MGAS38289_00246)	comYC	97985..98311 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
MGAS38289_RS00610 (MGAS38289_00248)	comGD	98286..98714 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
MGAS38289_RS00615 (MGAS38289_00250)	comGE	98671..98955 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
MGAS38289_RS00620 (MGAS38289_00252)	comYF	98948..99382 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGAS38289_RS00625 (MGAS38289_00254)	comGG	99366..99692 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
MGAS38289_RS00630 (MGAS38289_00256)	comYH	99790..100743 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
MGAS38289_RS00635 (MGAS38289_00258)	-	100802..101998 (+)	1197	WP_010921803.1	acetate kinase	-
MGAS38289_RS00640	-	102185..102493 (+)	309	WP_010921804.1	hypothetical protein	-
MGAS38289_RS00645 (MGAS38289_00260)	proC	102576..103346 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=976909 MGAS38289_RS00620 WP_010921800.1 98948..99382(+) (comYF) [Streptococcus pyogenes strain MGAS38289]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=976909 MGAS38289_RS00620 WP_010921800.1 98948..99382(+) (comYF) [Streptococcus pyogenes strain MGAS38289]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389