Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACAM23_RS02245 Genome accession   NZ_AP031394
Coordinates   416747..417379 (+) Length   210 a.a.
NCBI ID   WP_050218313.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P28     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 411747..422379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM23_RS02220 (SPNE16P28_04340) mvaD 412024..412977 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  ACAM23_RS02225 (SPNE16P28_04350) - 412964..413971 (+) 1008 WP_369608081.1 phosphomevalonate kinase -
  ACAM23_RS02230 (SPNE16P28_04360) fni 413955..414965 (+) 1011 WP_000210619.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ACAM23_RS02235 (SPNE16P28_04370) liaF 415043..415741 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  ACAM23_RS02240 (SPNE16P28_04380) - 415738..416733 (+) 996 WP_000743669.1 sensor histidine kinase -
  ACAM23_RS02245 (SPNE16P28_04390) vraR 416747..417379 (+) 633 WP_050218313.1 response regulator transcription factor Regulator
  ACAM23_RS02250 - 417455..418138 (+) 684 Protein_441 DNA alkylation repair protein -
  ACAM23_RS02255 (SPNE16P28_04420) - 418288..418527 (+) 240 WP_000754501.1 hypothetical protein -
  ACAM23_RS02260 (SPNE16P28_04430) cbpG 418608..419429 (+) 822 WP_050218312.1 choline-binding protein CbpG -
  ACAM23_RS02265 (SPNE16P28_04440) - 419448..420347 (+) 900 WP_050214867.1 choline-binding protein CbpF -
  ACAM23_RS02270 (SPNE16P28_04460) - 420475..421621 (-) 1147 Protein_445 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23552.04 Da        Isoelectric Point: 4.6387

>NTDB_id=97652 ACAM23_RS02245 WP_050218313.1 416747..417379(+) (vraR) [Streptococcus pneumoniae strain 16P28]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADNLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=97652 ACAM23_RS02245 WP_050218313.1 416747..417379(+) (vraR) [Streptococcus pneumoniae strain 16P28]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATAACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTACGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment