Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8522_RS01915 Genome accession   NZ_AP026916
Coordinates   367331..368020 (+) Length   229 a.a.
NCBI ID   WP_050123263.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 362331..373020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS01890 (PC0006_03860) gpsB 362440..362769 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8522_RS01900 (PC0006_03870) - 363255..364412 (+) 1158 WP_050123267.1 class I SAM-dependent RNA methyltransferase -
  R8522_RS01905 (PC0006_03880) mapZ 364425..365819 (+) 1395 WP_000039286.1 mid-cell-anchored protein MapZ -
  R8522_RS01910 (PC0006_03890) gndA 365895..367319 (+) 1425 WP_000158798.1 NADP-dependent phosphogluconate dehydrogenase -
  R8522_RS01915 (PC0006_03900) covR 367331..368020 (+) 690 WP_050123263.1 response regulator transcription factor Regulator
  R8522_RS01920 (PC0006_03910) cbpC 368118..369074 (+) 957 Protein_376 choline-binding protein CbpC -
  R8522_RS01925 (PC0006_03920) - 369192..370391 (-) 1200 WP_054367219.1 MFS transporter permease -
  R8522_RS01930 (PC0006_03930) - 370434..371309 (-) 876 WP_230688537.1 lanthionine synthetase LanC family protein -
  R8522_RS11470 - 371920..372087 (+) 168 Protein_379 transposase -
  R8522_RS11475 - 372127..372249 (+) 123 Protein_380 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26892.18 Da        Isoelectric Point: 6.9836

>NTDB_id=97623 R8522_RS01915 WP_050123263.1 367331..368020(+) (covR) [Streptococcus pneumoniae strain PZ900700006]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLTTLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=97623 R8522_RS01915 WP_050123263.1 367331..368020(+) (covR) [Streptococcus pneumoniae strain PZ900700006]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGACGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment