Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R8775_RS07325 Genome accession   NZ_AP026915
Coordinates   1418965..1420197 (-) Length   410 a.a.
NCBI ID   WP_001863391.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1413965..1425197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS07295 (PC0005_14420) - 1414152..1415120 (+) 969 WP_317680899.1 NAD(P)/FAD-dependent oxidoreductase -
  R8775_RS07300 (PC0005_14430) whiA 1415154..1416065 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  R8775_RS07305 (PC0005_14440) - 1416062..1417039 (-) 978 WP_001231086.1 YvcK family protein -
  R8775_RS07310 (PC0005_14450) rapZ 1417036..1417926 (-) 891 WP_000163033.1 RNase adapter RapZ -
  R8775_RS07315 (PC0005_14460) - 1417978..1418358 (-) 381 WP_001140412.1 RidA family protein -
  R8775_RS07320 (PC0005_14470) yihA 1418369..1418956 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R8775_RS07325 (PC0005_14480) clpX 1418965..1420197 (-) 1233 WP_001863391.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R8775_RS07330 - 1420229..1420399 (-) 171 WP_000442275.1 hypothetical protein -
  R8775_RS07335 (PC0005_14490) - 1420399..1420905 (-) 507 WP_050091052.1 dihydrofolate reductase -
  R8775_RS07340 (PC0005_14500) - 1421035..1421553 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  R8775_RS07345 (PC0005_14510) lytC 1422049..1423554 (-) 1506 WP_075575672.1 choline binding-anchored murein hydrolase LytC -
  R8775_RS07350 (PC0005_14520) tpiA 1423592..1424350 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  R8775_RS07355 (PC0005_14530) - 1424448..1425125 (-) 678 WP_000221611.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45740.31 Da        Isoelectric Point: 4.4775

>NTDB_id=97571 R8775_RS07325 WP_001863391.1 1418965..1420197(-) (clpX) [Streptococcus pneumoniae strain PZ900700005]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDANSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=97571 R8775_RS07325 WP_001863391.1 1418965..1420197(-) (clpX) [Streptococcus pneumoniae strain PZ900700005]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGCAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTAGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATTGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559

Multiple sequence alignment