Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8775_RS02065 Genome accession   NZ_AP026915
Coordinates   386686..387375 (+) Length   229 a.a.
NCBI ID   WP_000518010.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 381686..392375
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS02040 (PC0005_03970) gpsB 381795..382124 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8775_RS02050 (PC0005_03980) - 382610..383767 (+) 1158 WP_050233391.1 class I SAM-dependent RNA methyltransferase -
  R8775_RS02055 (PC0005_03990) mapZ 383780..385174 (+) 1395 WP_000039284.1 mid-cell-anchored protein MapZ -
  R8775_RS02060 (PC0005_04000) gndA 385250..386674 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  R8775_RS02065 (PC0005_04010) covR 386686..387375 (+) 690 WP_000518010.1 response regulator transcription factor Regulator
  R8775_RS02070 (PC0005_04020) cbpC 387473..388429 (+) 957 WP_050204373.1 choline-binding protein CbpC -
  R8775_RS02075 - 388548..389780 (-) 1233 WP_000765674.1 MFS transporter -
  R8775_RS02080 (PC0005_04050) - 389823..390410 (-) 588 WP_001835194.1 lanthionine synthetase LanC family protein -
  R8775_RS02085 - 390310..390648 (-) 339 Protein_410 lantibiotic-modifying protein -
  R8775_RS10750 - 391311..391478 (+) 168 Protein_411 transposase -
  R8775_RS10755 - 391518..391640 (+) 123 Protein_412 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26862.16 Da        Isoelectric Point: 6.9836

>NTDB_id=97548 R8775_RS02065 WP_000518010.1 386686..387375(+) (covR) [Streptococcus pneumoniae strain PZ900700005]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=97548 R8775_RS02065 WP_000518010.1 386686..387375(+) (covR) [Streptococcus pneumoniae strain PZ900700005]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTACAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment