Detailed information NTG0974985

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ36_RS09710
• Genome accession: NZ_CP151115
• Coordinates: 1979059..1980102 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN183
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1974059..1985102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ36_RS09680 (UXQ36_09680)	-	1974480..1975736 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ36_RS09685 (UXQ36_09685)	-	1975739..1975939 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ36_RS09690 (UXQ36_09690)	-	1976086..1976550 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ36_RS09695 (UXQ36_09695)	-	1976557..1976832 (+)	276	WP_341514585.1	YtxH domain-containing protein	-
UXQ36_RS09700 (UXQ36_09700)	-	1977110..1978327 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ36_RS09705 (UXQ36_09705)	vraR	1978440..1979069 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ36_RS09710 (UXQ36_09710)	vraS	1979059..1980102 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ36_RS09715 (UXQ36_09715)	liaF	1980099..1980800 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ36_RS09720 (UXQ36_09720)	-	1980815..1981201 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ36_RS09725 (UXQ36_09725)	map	1981418..1982176 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ36_RS09730 (UXQ36_09730)	-	1982648..1983634 (+)	987	WP_000999710.1	aromatic acid exporter family protein	-
UXQ36_RS09735 (UXQ36_09735)	-	1984065..1984478 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ36_RS09740 (UXQ36_09740)	-	1984507..1984617 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=974985 UXQ36_RS09710 WP_001017131.1 1979059..1980102(-) (vraS) [Staphylococcus aureus strain BSN183]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=974985 UXQ36_RS09710 WP_001017131.1 1979059..1980102(-) (vraS) [Staphylococcus aureus strain BSN183]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1