Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8474_RS01750 Genome accession   NZ_AP026914
Coordinates   339156..339845 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700003     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 334156..344845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8474_RS01725 (PC0003_03330) gpsB 334265..334594 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8474_RS01735 (PC0003_03340) - 335080..336237 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  R8474_RS01740 (PC0003_03350) mapZ 336250..337644 (+) 1395 WP_050205373.1 mid-cell-anchored protein MapZ -
  R8474_RS01745 (PC0003_03360) gndA 337720..339144 (+) 1425 WP_000158776.1 NADP-dependent phosphogluconate dehydrogenase -
  R8474_RS01750 (PC0003_03370) covR 339156..339845 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  R8474_RS01755 (PC0003_03380) cbpJ 339944..340942 (+) 999 WP_000771053.1 choline-binding protein CbpJ -
  R8474_RS01760 (PC0003_03390) - 341060..342292 (-) 1233 WP_000765680.1 MFS transporter -
  R8474_RS01765 (PC0003_03400) - 342451..343065 (-) 615 WP_307877808.1 lanthionine synthetase LanC family protein -
  R8474_RS10655 - 343821..343988 (+) 168 Protein_345 transposase -
  R8474_RS10660 - 344028..344150 (+) 123 Protein_346 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=97470 R8474_RS01750 WP_000518011.1 339156..339845(+) (covR) [Streptococcus pneumoniae strain PZ900700003]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=97470 R8474_RS01750 WP_000518011.1 339156..339845(+) (covR) [Streptococcus pneumoniae strain PZ900700003]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment