Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | UXR26_RS00280 | Genome accession | NZ_CP150888 |
| Coordinates | 62378..64006 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain BSN181 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57157..100881 | 62378..64006 | within | 0 |
| SCCmec | 44013..65377 | 62378..64006 | within | 0 |
Gene organization within MGE regions
Location: 44013..100881
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| UXR26_RS00185 (UXR26_00185) | mecA | 44013..46022 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| UXR26_RS00190 (UXR26_00190) | mecR1 | 46119..47876 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| UXR26_RS00195 (UXR26_00195) | mecI | 47876..48247 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| UXR26_RS00200 (UXR26_00200) | psm-mec | 48332..48400 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| UXR26_RS00205 (UXR26_00205) | - | 48733..49863 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| UXR26_RS00210 (UXR26_00210) | cstB | 49977..51311 (-) | 1335 | Protein_39 | persulfide dioxygenase-sulfurtransferase CstB | - |
| UXR26_RS00215 (UXR26_00215) | - | 51344..52408 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| UXR26_RS00220 (UXR26_00220) | cstR | 52544..52804 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| UXR26_RS00225 (UXR26_00225) | - | 52804..53442 (+) | 639 | Protein_42 | sulfite exporter TauE/SafE family protein | - |
| UXR26_RS00230 (UXR26_00230) | - | 53787..54449 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| UXR26_RS00235 (UXR26_00235) | erm(A) | 54983..55714 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| UXR26_RS00240 (UXR26_00240) | - | 55840..56622 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| UXR26_RS00245 (UXR26_00245) | - | 56773..57150 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| UXR26_RS00250 (UXR26_00250) | - | 57157..59049 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| UXR26_RS00255 (UXR26_00255) | - | 59046..60131 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| UXR26_RS00260 (UXR26_00260) | - | 60250..60567 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| UXR26_RS00265 (UXR26_00265) | - | 60588..61094 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| UXR26_RS00270 (UXR26_00270) | - | 61112..61423 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| UXR26_RS00275 (UXR26_00275) | - | 61510..61860 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| UXR26_RS00280 (UXR26_00280) | ccrB | 62378..64006 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| UXR26_RS00285 (UXR26_00285) | ccrA | 64028..65377 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| UXR26_RS00290 (UXR26_00290) | - | 65611..67404 (-) | 1794 | WP_000195105.1 | DUF927 domain-containing protein | - |
| UXR26_RS00295 (UXR26_00295) | - | 67404..67700 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| UXR26_RS00300 (UXR26_00300) | - | 67893..68939 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| UXR26_RS00305 (UXR26_00305) | - | 69190..70331 (-) | 1142 | Protein_58 | IS3-like element ISSau4 family transposase | - |
| UXR26_RS00310 (UXR26_00310) | - | 70842..71768 (-) | 927 | Protein_59 | YfcC family protein | - |
| UXR26_RS00315 (UXR26_00315) | - | 72489..73184 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| UXR26_RS00320 (UXR26_00320) | - | 73159..75828 (-) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| UXR26_RS00325 (UXR26_00325) | kdpF | 75995..76075 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| UXR26_RS00330 (UXR26_00330) | kdpA | 76096..77772 (+) | 1677 | WP_341276523.1 | potassium-transporting ATPase subunit KdpA | - |
| UXR26_RS00335 (UXR26_00335) | - | 77791..79812 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| UXR26_RS00340 (UXR26_00340) | - | 79828..80385 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| UXR26_RS00345 (UXR26_00345) | - | 80930..81799 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| UXR26_RS00350 (UXR26_00350) | - | 81809..82705 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| UXR26_RS00355 (UXR26_00355) | - | 83824..84450 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| UXR26_RS00360 (UXR26_00360) | - | 84565..86073 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| UXR26_RS00365 (UXR26_00365) | - | 86323..86457 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| UXR26_RS00370 (UXR26_00370) | - | 86421..86513 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| UXR26_RS00375 (UXR26_00375) | - | 86660..88405 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| UXR26_RS00380 (UXR26_00380) | - | 88503..88858 (-) | 356 | Protein_73 | tRNA-dihydrouridine synthase | - |
| UXR26_RS00385 (UXR26_00385) | - | 89163..89251 (-) | 89 | Protein_74 | hypothetical protein | - |
| UXR26_RS00390 (UXR26_00390) | - | 89349..90104 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| UXR26_RS00395 (UXR26_00395) | cstR | 90104..90364 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| UXR26_RS00400 (UXR26_00400) | cstA | 90501..91565 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| UXR26_RS00405 (UXR26_00405) | cstB | 91596..92930 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| UXR26_RS00410 (UXR26_00410) | sqr | 92949..94142 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| UXR26_RS00415 (UXR26_00415) | - | 94409..94623 (-) | 215 | Protein_80 | universal stress protein | - |
| UXR26_RS00420 (UXR26_00420) | - | 94809..95795 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| UXR26_RS00425 (UXR26_00425) | - | 96104..96307 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| UXR26_RS00430 (UXR26_00430) | - | 96356..96652 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| UXR26_RS00435 (UXR26_00435) | - | 96860..97462 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| UXR26_RS00440 (UXR26_00440) | - | 97729..100881 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=973471 UXR26_RS00280 WP_001186602.1 62378..64006(-) (ccrB) [Staphylococcus aureus strain BSN181]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=973471 UXR26_RS00280 WP_001186602.1 62378..64006(-) (ccrB) [Staphylococcus aureus strain BSN181]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |