Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   WNC56_RS17225 Genome accession   NZ_CP150833
Coordinates   3326402..3327577 (-) Length   391 a.a.
NCBI ID   WP_060698460.1    Uniprot ID   -
Organism   Bacillus safensis strain DMB13     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 3306140..3325433 3326402..3327577 flank 969


Gene organization within MGE regions


Location: 3306140..3327577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WNC56_RS17120 (WNC56_17090) - 3306140..3306559 (-) 420 WP_024423621.1 TIGR03826 family flagellar region protein -
  WNC56_RS17125 (WNC56_17095) comFC 3306616..3307050 (-) 435 WP_051170133.1 ComF family protein Machinery gene
  WNC56_RS17130 (WNC56_17100) - 3307299..3307592 (-) 294 WP_041088040.1 late competence development ComFB family protein -
  WNC56_RS17135 (WNC56_17105) epsC 3307917..3308765 (-) 849 WP_254965332.1 serine O-acetyltransferase EpsC -
  WNC56_RS17140 (WNC56_17110) pyrH 3308866..3309606 (+) 741 WP_254965331.1 UMP kinase -
  WNC56_RS17145 (WNC56_17115) - 3309662..3310840 (-) 1179 WP_254965329.1 MFS transporter -
  WNC56_RS17150 (WNC56_17120) - 3310903..3311823 (-) 921 WP_254965327.1 phosphotransferase -
  WNC56_RS17155 (WNC56_17125) - 3311838..3313022 (-) 1185 WP_406845871.1 ATP-grasp domain-containing protein -
  WNC56_RS17160 (WNC56_17130) - 3313015..3314235 (-) 1221 WP_254965324.1 acetyl-CoA carboxylase biotin carboxylase subunit family protein -
  WNC56_RS17165 (WNC56_17135) - 3314246..3315841 (-) 1596 WP_254965322.1 class I adenylate-forming enzyme family protein -
  WNC56_RS17170 (WNC56_17140) - 3315881..3316138 (-) 258 WP_254965320.1 acyl carrier protein -
  WNC56_RS17175 (WNC56_17145) - 3316135..3316857 (-) 723 WP_254965319.1 SDR family NAD(P)-dependent oxidoreductase -
  WNC56_RS17180 (WNC56_17150) - 3316858..3317826 (-) 969 WP_254965317.1 alpha/beta hydrolase -
  WNC56_RS17185 (WNC56_17155) - 3317831..3319348 (-) 1518 WP_254965315.1 NAD(P)-dependent oxidoreductase -
  WNC56_RS17190 (WNC56_17160) - 3319363..3320058 (-) 696 WP_254965312.1 hypothetical protein -
  WNC56_RS17195 (WNC56_17165) - 3320070..3320918 (-) 849 WP_254965310.1 NAD(P)-dependent oxidoreductase -
  WNC56_RS17200 (WNC56_17170) - 3320922..3322397 (-) 1476 WP_254965308.1 nucleoside monophosphate kinase -
  WNC56_RS17205 (WNC56_17175) - 3322394..3323506 (-) 1113 WP_254965306.1 nucleotidyltransferase family protein -
  WNC56_RS17210 (WNC56_17180) - 3323503..3323805 (-) 303 WP_254965304.1 Dabb family protein -
  WNC56_RS17215 (WNC56_17185) - 3324591..3325433 (-) 843 WP_406845872.1 DegV family protein -
  WNC56_RS17220 (WNC56_17190) degU 3325648..3326337 (-) 690 WP_008348273.1 two-component system response regulator DegU Regulator
  WNC56_RS17225 (WNC56_17195) degS 3326402..3327577 (-) 1176 WP_060698460.1 sensor histidine kinase Regulator

Sequence

Protein


Download         Length: 391 a.a.        Molecular weight: 45509.22 Da        Isoelectric Point: 5.8757

>NTDB_id=972803 WNC56_RS17225 WP_060698460.1 3326402..3327577(-) (degS) [Bacillus safensis strain DMB13]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTESERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLSLQNKIVK

Nucleotide


Download         Length: 1176 bp        

>NTDB_id=972803 WNC56_RS17225 WP_060698460.1 3326402..3327577(-) (degS) [Bacillus safensis strain DMB13]
ATGACAACACCCAAAATGGATCCGAAATTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGCAAGGA
CGAAGTATTTAGAATAGGCGAACAGTCCCGTCAACAATATGAAAGCCTAGTAGAAGAGCTCAAGCAAATCAAGCAGCAAG
TAAACGAAGTAATTGATTTTGGGGACAAGCTGGAAGTCCATACAAGACATGCTAGAAATCGCTTATCTGAGGTCAGCAGA
AACTTCAACAAATTCAGCGAAGAAGAAATACGTGAGGCCTACGAAAAAGCACATAACTTGCAAGTGGAACTCACCATGAT
CCAGCAGCGTGAGAAGCAGCTGAGAGAAAGAAGAGACGATCTGGAAAGACGATTATTAAGCTTACAAGACGTCATTGAGC
GTTCTGAAACGCTTGTGAGTCAGATTACAGTGGTTCTCAACTATCTCAACCAGGATTTACGCCAGGTCGGCGTTTTACTT
GAAGATGCTCAGGCAAAACAAGATTTTGGGCTGAGAATTATTGAAGCCCAAGAAGAAGAACGCAAAAGAGTGTCTCGGGA
AATTCATGACGGCCCTGCTCAAATGCTGGCAAACGTGATGATGCGTTCCGAATTAATTGAACGAATTTTTAGAGACCGCG
GTACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTCAGACAGAATGTGCGGAATGCACTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCGATGGCTTTAGATGATTTGGGTCTGATTCCGACACTGAGAAAATACTTAAACACAATTGAAGAATA
TGATGGGAAAACCAAAATTACGTTCCAATGCCTAGGTGATACAGAAAGCGAAAGAATTGCTTCTCAATTTGAAGTAGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTAAAGCATTCTGAAGCTGAAGAAATCTCTGTCAAAGTAGAAGTA
ACGAAAGACTTTGTGACCTTAATTATTAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAACAAAAACAA
ATCCTTCGGTTTACTTGGCATGAAAGAACGCGTAGACTTACTGGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTCATCATGATTCGCGTGCCATTATCATTGCAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

Sensor protein DegS (DegS)

(12-170)

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

85.714

98.465

0.844

Multiple sequence alignment