Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   WOC64_RS11075 Genome accession   NZ_CP150788
Coordinates   2234432..2235001 (+) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain TUM20816     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2229432..2240001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC64_RS11040 (WOC64_11035) - 2230640..2230912 (-) 273 WP_001790097.1 lactococcin 972 family bacteriocin -
  WOC64_RS11045 (WOC64_11040) - 2230922..2231023 (-) 102 WP_001790623.1 hypothetical protein -
  WOC64_RS11050 - 2231562..2231639 (-) 78 WP_099112139.1 putative holin-like toxin -
  WOC64_RS11055 (WOC64_11050) - 2231940..2232544 (-) 605 Protein_2152 type II CAAX prenyl endopeptidase Rce1 family protein -
  WOC64_RS11060 (WOC64_11055) - 2232559..2232735 (-) 177 WP_000214898.1 YkvS family protein -
  WOC64_RS11065 (WOC64_11060) - 2232934..2233923 (+) 990 Protein_2154 lipoate--protein ligase -
  WOC64_RS11070 (WOC64_11065) - 2234004..2234222 (-) 219 WP_000876826.1 IDEAL domain-containing protein -
  WOC64_RS11075 (WOC64_11070) comK/comK1 2234432..2235001 (+) 570 WP_000287265.1 competence protein ComK Regulator
  WOC64_RS11090 (WOC64_11085) - 2235488..2236998 (-) 1511 Protein_2157 bifunctional metallophosphatase/5'-nucleotidase -
  WOC64_RS11095 (WOC64_11090) - 2237137..2238495 (-) 1359 WP_000021864.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=972676 WOC64_RS11075 WP_000287265.1 2234432..2235001(+) (comK/comK1) [Staphylococcus aureus strain TUM20816]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=972676 WOC64_RS11075 WP_000287265.1 2234432..2235001(+) (comK/comK1) [Staphylococcus aureus strain TUM20816]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1

Multiple sequence alignment