Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACL656_RS09125 Genome accession   NZ_CP178597
Coordinates   1930777..1931433 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ZF8-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1925777..1936433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL656_RS09090 (ACL656_09090) dcyD 1926656..1927642 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACL656_RS09095 (ACL656_09095) tcyL 1927657..1928325 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACL656_RS09100 (ACL656_09100) tcyN 1928322..1929074 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACL656_RS09105 (ACL656_09105) sdiA 1929304..1930026 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  ACL656_RS09110 (ACL656_09110) yecF 1930094..1930318 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACL656_RS09115 (ACL656_09115) yecU 1930305..1930481 (-) 177 WP_001302050.1 protein YecU -
  ACL656_RS09120 (ACL656_09120) - 1930519..1930635 (-) 117 WP_001302039.1 hypothetical protein -
  ACL656_RS09125 (ACL656_09125) letA 1930777..1931433 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACL656_RS09130 (ACL656_09130) uvrC 1931430..1933262 (+) 1833 WP_001283415.1 excinuclease ABC subunit UvrC Machinery gene
  ACL656_RS09135 (ACL656_09135) pgsA 1933319..1933867 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACL656_RS09155 (ACL656_09155) yecA 1934516..1935181 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=972499 ACL656_RS09125 WP_000611328.1 1930777..1931433(+) (letA) [Escherichia coli strain ZF8-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=972499 ACL656_RS09125 WP_000611328.1 1930777..1931433(+) (letA) [Escherichia coli strain ZF8-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGATGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482