Detailed information NTG0972327

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC60_RS09825
• Genome accession: NZ_CP150771
• Coordinates: 2003530..2004573 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20914
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1998530..2009573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC60_RS09795 (WOC60_09805)	-	1998948..2000204 (-)	1257	WP_108932452.1	aminopeptidase	-
WOC60_RS09800 (WOC60_09810)	-	2000207..2000407 (-)	201	WP_000180461.1	DUF1128 family protein	-
WOC60_RS09805 (WOC60_09815)	-	2000554..2001018 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC60_RS09810 (WOC60_09820)	-	2001025..2001300 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC60_RS09815 (WOC60_09825)	-	2001578..2002795 (+)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
WOC60_RS09820 (WOC60_09830)	vraR	2002911..2003540 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WOC60_RS09825 (WOC60_09835)	vraS	2003530..2004573 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC60_RS09830 (WOC60_09840)	liaF	2004570..2005271 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC60_RS09835 (WOC60_09845)	-	2005286..2005672 (-)	387	WP_001110179.1	hypothetical protein	-
WOC60_RS09840 (WOC60_09850)	map	2005889..2006647 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC60_RS09845 (WOC60_09855)	-	2007234..2008220 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC60_RS09850 (WOC60_09860)	-	2008651..2009064 (-)	414	WP_001549145.1	hypothetical protein	-
WOC60_RS09855 (WOC60_09865)	-	2009093..2009203 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=972327 WOC60_RS09825 WP_001017131.1 2003530..2004573(-) (vraS) [Staphylococcus aureus strain TUM20914]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=972327 WOC60_RS09825 WP_001017131.1 2003530..2004573(-) (vraS) [Staphylococcus aureus strain TUM20914]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1