Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   WOC74_RS12510 Genome accession   NZ_CP150759
Coordinates   2523428..2523997 (+) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain TUM22178     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2518428..2528997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC74_RS12485 (WOC74_12465) cysE 2519641..2520288 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  WOC74_RS12490 (WOC74_12470) cysS 2520272..2521672 (+) 1401 WP_000631973.1 cysteine--tRNA ligase -
  WOC74_RS12495 (WOC74_12475) - 2521665..2522069 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  WOC74_RS12500 (WOC74_12480) rlmB 2522077..2522823 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  WOC74_RS12505 (WOC74_12485) - 2522823..2523347 (+) 525 WP_000664738.1 NYN domain-containing protein -
  WOC74_RS12510 (WOC74_12490) sigH 2523428..2523997 (+) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  WOC74_RS12515 (WOC74_12495) rpmG 2524112..2524255 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  WOC74_RS12520 (WOC74_12500) secE 2524311..2524493 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  WOC74_RS12525 (WOC74_12505) nusG 2524506..2525054 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  WOC74_RS12530 (WOC74_12510) rplK 2525235..2525657 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  WOC74_RS12535 (WOC74_12515) rplA 2525865..2526557 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  WOC74_RS12540 (WOC74_12520) rplJ 2526829..2527329 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  WOC74_RS12545 (WOC74_12525) rplL 2527372..2527740 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  WOC74_RS12550 (WOC74_12530) - 2527915..2528523 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=972029 WOC74_RS12510 WP_000872877.1 2523428..2523997(+) (sigH) [Staphylococcus aureus strain TUM22178]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=972029 WOC74_RS12510 WP_000872877.1 2523428..2523997(+) (sigH) [Staphylococcus aureus strain TUM22178]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment