Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   WOC65_RS12370 Genome accession   NZ_CP150756
Coordinates   2493839..2494408 (-) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain TUM22188     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2488839..2499408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC65_RS12330 (WOC65_12310) - 2489313..2489921 (-) 609 WP_000020302.1 class I SAM-dependent methyltransferase -
  WOC65_RS12335 (WOC65_12315) rplL 2490096..2490464 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  WOC65_RS12340 (WOC65_12320) rplJ 2490507..2491007 (-) 501 WP_001273087.1 50S ribosomal protein L10 -
  WOC65_RS12345 (WOC65_12325) rplA 2491279..2491971 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  WOC65_RS12350 (WOC65_12330) rplK 2492179..2492601 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  WOC65_RS12355 (WOC65_12335) nusG 2492782..2493330 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  WOC65_RS12360 (WOC65_12340) secE 2493343..2493525 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  WOC65_RS12365 (WOC65_12345) rpmG 2493581..2493724 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  WOC65_RS12370 (WOC65_12350) sigH 2493839..2494408 (-) 570 WP_000872877.1 sigma-70 family RNA polymerase sigma factor Regulator
  WOC65_RS12375 (WOC65_12355) - 2494489..2495013 (-) 525 WP_000664738.1 NYN domain-containing protein -
  WOC65_RS12380 (WOC65_12360) rlmB 2495013..2495759 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  WOC65_RS12385 (WOC65_12365) - 2495767..2496171 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  WOC65_RS12390 (WOC65_12370) cysS 2496164..2497564 (-) 1401 WP_000631973.1 cysteine--tRNA ligase -
  WOC65_RS12395 (WOC65_12375) cysE 2497548..2498195 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=971940 WOC65_RS12370 WP_000872877.1 2493839..2494408(-) (sigH) [Staphylococcus aureus strain TUM22188]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=971940 WOC65_RS12370 WP_000872877.1 2493839..2494408(-) (sigH) [Staphylococcus aureus strain TUM22188]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment