Detailed information NTG0971837

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC45_RS08005
• Genome accession: NZ_CP150752
• Coordinates: 1560043..1560930 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain TUM22458
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1555043..1565930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC45_RS07975 (WOC45_07980)	-	1555062..1555154 (+)	93	WP_010956583.1	hypothetical protein	-
WOC45_RS07980 (WOC45_07985)	-	1555262..1555759 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC45_RS07985 (WOC45_07990)	-	1555769..1556029 (-)	261	WP_001791974.1	hypothetical protein	-
WOC45_RS07990 (WOC45_07995)	-	1556411..1556524 (-)	114	Protein_1578	hypothetical protein	-
WOC45_RS07995 (WOC45_08000)	-	1557183..1559183 (-)	2001	WP_000776751.1	ABC transporter permease	-
WOC45_RS08000 (WOC45_08005)	-	1559180..1559935 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC45_RS08005 (WOC45_08010)	braS	1560043..1560930 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC45_RS08010 (WOC45_08015)	braR	1560941..1561606 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC45_RS08015 (WOC45_08020)	-	1561632..1561832 (-)	201	WP_000604730.1	hypothetical protein	-
WOC45_RS08020 (WOC45_08025)	-	1562030..1563454 (+)	1425	WP_000953755.1	alkaline phosphatase	-
WOC45_RS08025	-	1563514..1563615 (-)	102	WP_000731976.1	SE2200 family small protein	-
WOC45_RS08030 (WOC45_08035)	-	1563737..1564192 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC45_RS08035 (WOC45_08040)	-	1564437..1565198 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971837 WOC45_RS08005 WP_000143425.1 1560043..1560930(-) (braS) [Staphylococcus aureus strain TUM22458]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971837 WOC45_RS08005 WP_000143425.1 1560043..1560930(-) (braS) [Staphylococcus aureus strain TUM22458]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1