Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   WOC43_RS10235 Genome accession   NZ_CP150749
Coordinates   2061564..2062250 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain TUM22699     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2056564..2067250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC43_RS10200 (WOC43_10200) yqeH 2057091..2058191 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  WOC43_RS10205 (WOC43_10205) aroE 2058205..2059011 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  WOC43_RS10210 (WOC43_10210) yhbY 2059015..2059305 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  WOC43_RS10215 (WOC43_10215) nadD 2059308..2059877 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  WOC43_RS10220 (WOC43_10220) yqeK 2059867..2060451 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  WOC43_RS10225 (WOC43_10225) rsfS 2060452..2060805 (+) 354 WP_001088022.1 ribosome silencing factor -
  WOC43_RS10230 (WOC43_10230) - 2060808..2061524 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  WOC43_RS10235 (WOC43_10235) comEA 2061564..2062250 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  WOC43_RS10240 (WOC43_10240) - 2062342..2062803 (+) 462 WP_000439693.1 ComE operon protein 2 -
  WOC43_RS10245 (WOC43_10245) - 2062808..2065011 (+) 2204 Protein_1970 DNA internalization-related competence protein ComEC/Rec2 -
  WOC43_RS10250 (WOC43_10250) holA 2065068..2066042 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  WOC43_RS10255 (WOC43_10255) rpsT 2066087..2066338 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=971754 WOC43_RS10235 WP_001792568.1 2061564..2062250(+) (comEA) [Staphylococcus aureus strain TUM22699]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=971754 WOC43_RS10235 WP_001792568.1 2061564..2062250(+) (comEA) [Staphylococcus aureus strain TUM22699]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment