Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACL09D_RS01145 Genome accession   NZ_CP178401
Coordinates   221767..222423 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain N1286     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 216767..227423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL09D_RS01115 (ACL09D_01115) yecA 218019..218684 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ACL09D_RS01135 (ACL09D_01135) pgsA 219333..219881 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACL09D_RS01140 (ACL09D_01140) uvrC 219938..221770 (-) 1833 WP_001283426.1 excinuclease ABC subunit UvrC Machinery gene
  ACL09D_RS01145 (ACL09D_01145) letA 221767..222423 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACL09D_RS01150 (ACL09D_01150) - 222565..222636 (+) 72 Protein_225 transcriptional regulator -
  ACL09D_RS01155 (ACL09D_01155) yecU 222719..222895 (+) 177 WP_001307856.1 protein YecU -
  ACL09D_RS01160 (ACL09D_01160) yecF 222882..223106 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACL09D_RS01165 (ACL09D_01165) sdiA 223173..223895 (-) 723 WP_001154266.1 transcriptional regulator SdiA -
  ACL09D_RS01170 (ACL09D_01170) tcyN 224125..224877 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACL09D_RS01175 (ACL09D_01175) tcyL 224874..225542 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACL09D_RS01180 (ACL09D_01180) dcyD 225557..226543 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=971746 ACL09D_RS01145 WP_000611328.1 221767..222423(-) (letA) [Escherichia coli strain N1286]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=971746 ACL09D_RS01145 WP_000611328.1 221767..222423(-) (letA) [Escherichia coli strain N1286]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment