Detailed information NTG0971674

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC69_RS13285
• Genome accession: NZ_CP150744
• Coordinates: 2655340..2656383 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22702
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2650340..2661383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC69_RS13255 (WOC69_13255)	-	2650766..2650876 (+)	111	WP_001790257.1	hypothetical protein	-
WOC69_RS13260 (WOC69_13260)	-	2650905..2651318 (+)	414	WP_001557448.1	hypothetical protein	-
WOC69_RS13265 (WOC69_13265)	-	2651749..2652735 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
WOC69_RS13270 (WOC69_13270)	map	2653266..2654024 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC69_RS13275 (WOC69_13275)	-	2654241..2654627 (+)	387	WP_001110179.1	hypothetical protein	-
WOC69_RS13280 (WOC69_13280)	liaF	2654642..2655343 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC69_RS13285 (WOC69_13285)	vraS	2655340..2656383 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC69_RS13290 (WOC69_13290)	vraR	2656373..2657002 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC69_RS13295 (WOC69_13295)	-	2657115..2658332 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
WOC69_RS13300 (WOC69_13300)	-	2658610..2658885 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC69_RS13305 (WOC69_13305)	-	2658892..2659356 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC69_RS13310 (WOC69_13310)	-	2659503..2659703 (+)	201	WP_000180460.1	DUF1128 family protein	-
WOC69_RS13315 (WOC69_13315)	-	2659706..2660962 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=971674 WOC69_RS13285 WP_001017131.1 2655340..2656383(+) (vraS) [Staphylococcus aureus strain TUM22702]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=971674 WOC69_RS13285 WP_001017131.1 2655340..2656383(+) (vraS) [Staphylococcus aureus strain TUM22702]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1