Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   WOC46_RS07335 Genome accession   NZ_CP150733
Coordinates   1477556..1478242 (+) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain TUM22741     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1472556..1483242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC46_RS07300 (WOC46_07300) yqeH 1473083..1474183 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  WOC46_RS07305 (WOC46_07305) aroE 1474197..1475003 (+) 807 WP_000666748.1 shikimate dehydrogenase -
  WOC46_RS07310 (WOC46_07310) yhbY 1475007..1475297 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  WOC46_RS07315 (WOC46_07315) nadD 1475300..1475869 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  WOC46_RS07320 (WOC46_07320) yqeK 1475859..1476443 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  WOC46_RS07325 (WOC46_07325) rsfS 1476444..1476797 (+) 354 WP_001088022.1 ribosome silencing factor -
  WOC46_RS07330 (WOC46_07330) - 1476800..1477516 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  WOC46_RS07335 (WOC46_07335) comEA 1477556..1478242 (+) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  WOC46_RS07340 (WOC46_07340) - 1478334..1478795 (+) 462 WP_000439693.1 ComE operon protein 2 -
  WOC46_RS07345 (WOC46_07345) comEC 1478800..1481001 (+) 2202 WP_341261278.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  WOC46_RS07350 (WOC46_07350) holA 1481058..1482032 (+) 975 WP_001282568.1 DNA polymerase III subunit delta -
  WOC46_RS07355 (WOC46_07355) rpsT 1482077..1482328 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=971393 WOC46_RS07335 WP_001793467.1 1477556..1478242(+) (comEA) [Staphylococcus aureus strain TUM22741]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=971393 WOC46_RS07335 WP_001793467.1 1477556..1478242(+) (comEA) [Staphylococcus aureus strain TUM22741]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974

Multiple sequence alignment