Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACLFAM_RS11955 Genome accession   NZ_CP178226
Coordinates   2376396..2377631 (+) Length   411 a.a.
NCBI ID   WP_012897750.1    Uniprot ID   -
Organism   Lactococcus lactis strain L-WY410     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2371396..2382631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLFAM_RS11925 (ACLFAM_11925) - 2372233..2372826 (+) 594 WP_003132093.1 xanthine phosphoribosyltransferase -
  ACLFAM_RS11930 (ACLFAM_11930) - 2372875..2374179 (+) 1305 WP_003132095.1 nucleobase:cation symporter-2 family protein -
  ACLFAM_RS11935 (ACLFAM_11935) - 2374207..2374494 (-) 288 WP_223247175.1 hypothetical protein -
  ACLFAM_RS11940 (ACLFAM_11940) - 2374491..2374619 (-) 129 WP_268988337.1 hypothetical protein -
  ACLFAM_RS11945 (ACLFAM_11945) - 2374739..2375248 (-) 510 WP_010905785.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  ACLFAM_RS11950 (ACLFAM_11950) - 2375646..2376152 (+) 507 WP_010905786.1 dihydrofolate reductase -
  ACLFAM_RS11955 (ACLFAM_11955) clpX 2376396..2377631 (+) 1236 WP_012897750.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACLFAM_RS11960 (ACLFAM_11960) yihA 2377628..2378215 (+) 588 WP_010905788.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACLFAM_RS11965 (ACLFAM_11965) folB 2378269..2378619 (+) 351 WP_003132106.1 dihydroneopterin aldolase -
  ACLFAM_RS11970 (ACLFAM_11970) folE 2378699..2379748 (+) 1050 WP_039115398.1 GTP cyclohydrolase I FolE -
  ACLFAM_RS11975 (ACLFAM_11975) folP 2379745..2380818 (+) 1074 WP_003132109.1 dihydropteroate synthase -
  ACLFAM_RS11980 (ACLFAM_11980) - 2380821..2381318 (+) 498 WP_039115401.1 NUDIX domain-containing protein -
  ACLFAM_RS11985 (ACLFAM_11985) - 2381337..2382620 (+) 1284 WP_017864445.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 46024.89 Da        Isoelectric Point: 4.6053

>NTDB_id=971060 ACLFAM_RS11955 WP_012897750.1 2376396..2377631(+) (clpX) [Lactococcus lactis strain L-WY410]
MSNTQNPNIHCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=971060 ACLFAM_RS11955 WP_012897750.1 2376396..2377631(+) (clpX) [Lactococcus lactis strain L-WY410]
ATGTCAAATACACAAAATCCAAATATACATTGTTCTTTCTGTGGAAAGAGTCAAGATGATGTAAAAAAAATGATTGCCGG
TTCAGACGTTTATATTTGTAATGAATGTATTGAACTTTCAACTCGAATCTTAGAAGAAGAATTAAGAGAAGAACAAGATT
CAGAAATGCTTGAAGTTAAAACACCTAAAGAAATGTTTGACCATTTAAATGAGTACGTGATAGGTCAAGAAAAAGCAAAA
CGTGCACTTGCAGTTGCCGTTTATAATCATTACAAACGAATTAATTTTACAGCAAGTAAAATTGCTGAAGATATTGAACT
ACAAAAATCAAACATTCTATTAATCGGACCTACCGGTTCTGGTAAGACTTTTCTCGCTCAAACTTTAGCGAAATCACTCA
ACGTTCCATTTGCGATTGCAGATGCGACAAGTTTGACTGAAGCTGGTTATGTTGGAGAAGACGTTGAAAATATTCTCTTA
AAACTTTTACAAGCGAGTGATTTCAATATTGAACGTGCTGAACGTGGAATTATCTATATCGATGAAATTGATAAAATTGC
TAAAAAATCTGAAAATGTATCAATTACTCGTGACGTTTCCGGGGAAGGTGTTCAACAAGCCCTTTTGAAAATTATTGAAG
GGACAGTAGCTAGCGTTCCACCACAAGGTGGACGTAAACATCCTAATCAAGAAATGATTCAAATTGATACCAAAAATATC
TTATTTATCGTTGGTGGAGCTTTTGACGGGATTGAAGAAATTGTCAAACAACGTTTAGGTGAAAAAATTATTGGTTTTGG
TGCCAATAATAAAAAATTAAATGACGATGATTCTTATATGCAAGAAATTATTGCCGAGGACATTCAAAAATTCGGATTAA
TCCCTGAATTTATTGGTCGTCTGCCAATTGTTGCTGCTTTGGAGCGTTTGACCGAAGAAGATTTGATTCAAATTTTGACA
GAACCTAAAAACGCTTTGATTAAACAATATAAACAACTCCTTTTATTTGATAATGTTGAACTTGAATTTGAAGATGAAGC
CCTCATGGCAATTGCTAGAAAAGCAATTGAGCGCAAAACAGGAGCGCGTGGACTTCGTTCAATTATTGAAGAAGTAATGA
TGGATATCATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATTATTAATGAAGCAGTTGTTGACGGAAAAGCT
GAGCCACAAATGATTCGAGAGGCCAAGAAAAAATGA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(108-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(10-46)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(310-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

76.808

97.567

0.749
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.883

95.864

0.564