Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACJWMD_RS08235 Genome accession   NZ_CP177182
Coordinates   1745026..1747131 (-) Length   701 a.a.
NCBI ID   WP_004183275.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1740026..1752131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS08200 pptB 1740368..1741405 (-) 1038 WP_004183264.1 ABC transporter permease Regulator
  ACJWMD_RS08205 pptA 1741402..1742133 (-) 732 WP_004183266.1 ABC transporter ATP-binding protein Regulator
  ACJWMD_RS08210 - 1742198..1742617 (+) 420 WP_004183267.1 HIT family protein -
  ACJWMD_RS08215 - 1742614..1742913 (+) 300 WP_004183269.1 hypothetical protein -
  ACJWMD_RS08220 - 1743380..1743745 (-) 366 WP_156209922.1 hypothetical protein -
  ACJWMD_RS08225 - 1743838..1744446 (-) 609 WP_002884297.1 DUF4230 domain-containing protein -
  ACJWMD_RS08230 - 1744464..1744589 (-) 126 WP_002884447.1 hypothetical protein -
  ACJWMD_RS08235 clpE 1745026..1747131 (-) 2106 WP_004183275.1 AAA family ATPase Regulator
  ACJWMD_RS08240 - 1747865..1748956 (-) 1092 WP_004183282.1 nucleotidyltransferase -
  ACJWMD_RS08245 - 1748963..1749703 (-) 741 WP_004183284.1 class I SAM-dependent DNA methyltransferase -
  ACJWMD_RS08250 rsfS 1749868..1750218 (-) 351 WP_002891669.1 ribosome silencing factor -
  ACJWMD_RS08255 - 1750233..1750733 (-) 501 WP_004183286.1 cysteine hydrolase family protein -
  ACJWMD_RS08260 yqeK 1750737..1751330 (-) 594 WP_004183288.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACJWMD_RS08265 - 1751327..1751959 (-) 633 WP_004183290.1 nicotinate-nucleotide adenylyltransferase -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77324.26 Da        Isoelectric Point: 4.7435

>NTDB_id=969862 ACJWMD_RS08235 WP_004183275.1 1745026..1747131(-) (clpE) [Streptococcus salivarius strain MRD6060]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=969862 ACJWMD_RS08235 WP_004183275.1 1745026..1747131(-) (clpE) [Streptococcus salivarius strain MRD6060]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAATATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCGATTTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAATAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAA
AACGCTGCCCTAGCCCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATTGTTCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.79

100

0.468
  clpC Lactococcus lactis subsp. cremoris KW2

49.002

92.867

0.455
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpC Bacillus subtilis subsp. subtilis str. 168

45.666

92.154

0.421
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.089

92.867

0.391
  clpC Streptococcus pneumoniae TIGR4

43.087

88.73

0.382
  clpC Streptococcus pneumoniae Rx1

43.087

88.73

0.382
  clpC Streptococcus pneumoniae D39

43.087

88.73

0.382
  clpC Streptococcus thermophilus LMD-9

43.436

88.017

0.382
  clpC Streptococcus thermophilus LMG 18311

42.973

88.302

0.379
  clpC Streptococcus mutans UA159

42.332

89.301

0.378