Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACJWMC_RS10785 Genome accession   NZ_CP177181
Coordinates   2266788..2267540 (+) Length   250 a.a.
NCBI ID   WP_037598687.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD1919     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2261788..2272540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS10750 - 2262368..2263348 (-) 981 WP_002892291.1 caspase domain-containing protein -
  ACJWMC_RS10755 - 2263359..2263736 (-) 378 WP_002892294.1 TIR domain-containing protein -
  ACJWMC_RS10760 - 2263790..2264353 (-) 564 WP_002892296.1 hypothetical protein -
  ACJWMC_RS10765 - 2264486..2264718 (+) 233 Protein_2069 peptidylprolyl isomerase -
  ACJWMC_RS10770 - 2264765..2264911 (+) 147 Protein_2070 site-specific integrase -
  ACJWMC_RS10775 - 2264955..2265809 (-) 855 WP_002892298.1 hypothetical protein -
  ACJWMC_RS10780 - 2266062..2266208 (-) 147 WP_224111196.1 hypothetical protein -
  ACJWMC_RS10785 comE/blpR 2266788..2267540 (+) 753 WP_037598687.1 response regulator transcription factor Regulator
  ACJWMC_RS10790 - 2267676..2269523 (+) 1848 WP_002892302.1 SH3 domain-containing protein -
  ACJWMC_RS10795 - 2269652..2270218 (+) 567 WP_002892304.1 hypothetical protein -
  ACJWMC_RS10800 tnpA 2270405..2270878 (+) 474 Protein_2076 IS200/IS605 family transposase -
  ACJWMC_RS10805 - 2271062..2271313 (+) 252 WP_050989616.1 transposase -
  ACJWMC_RS10810 - 2271341..2271903 (+) 563 Protein_2078 hypothetical protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28708.18 Da        Isoelectric Point: 5.3920

>NTDB_id=969778 ACJWMC_RS10785 WP_037598687.1 2266788..2267540(+) (comE/blpR) [Streptococcus salivarius strain MRD1919]
MLDIFVLEEDYFQQARLEDAIHKSKQIYILRIGKVDLYDKPNQLLERITERGSHLLFFLDIGSDSDVEGGILVAQQIRER
DPYASIVFITAHPELLPSTFQYRLAALDFIDKNLPDIEYEDRIISDIGLALSKNGLSQIECAFTIDTKNATIQVPFHKIL
YFETSPTVHKVILHTTEEQIEFYGQLSKVVKQDCRLYKCHKSFVVNPENIVRLDKELGIIYFENGESCLVSKAKQKEIVA
KMLVPKPMAV

Nucleotide


Download         Length: 753 bp        

>NTDB_id=969778 ACJWMC_RS10785 WP_037598687.1 2266788..2267540(+) (comE/blpR) [Streptococcus salivarius strain MRD1919]
ATGTTAGATATTTTTGTTTTAGAAGAAGATTATTTTCAACAAGCTCGTCTTGAGGATGCCATCCACAAGTCTAAACAAAT
ATATATTTTAAGAATTGGGAAGGTTGATTTATACGATAAACCCAATCAATTATTAGAGCGTATTACGGAAAGGGGCTCGC
ATTTACTGTTTTTTCTAGATATTGGATCTGACAGTGATGTCGAAGGGGGAATATTGGTTGCTCAACAGATTCGTGAGCGA
GATCCGTATGCAAGTATTGTTTTCATCACAGCACATCCCGAACTCCTACCTTCAACCTTTCAGTATCGCTTAGCTGCACT
TGATTTTATTGACAAGAATTTGCCTGATATTGAATATGAAGATAGGATTATTTCTGATATTGGATTAGCACTTTCTAAAA
ATGGTCTGAGCCAAATAGAGTGTGCTTTTACTATAGATACAAAGAATGCAACTATACAAGTTCCTTTTCATAAGATACTC
TATTTTGAAACATCTCCAACAGTTCATAAGGTAATTCTTCATACAACAGAAGAGCAAATTGAGTTCTATGGTCAATTATC
AAAAGTTGTGAAACAAGATTGCAGACTATATAAATGCCATAAATCATTTGTTGTAAATCCCGAAAACATTGTGAGATTGG
ACAAAGAGTTAGGTATTATTTATTTTGAAAACGGAGAGTCATGCTTGGTTTCAAAAGCTAAACAAAAAGAGATTGTTGCT
AAGATGCTTGTTCCAAAACCCATGGCAGTTTGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

45.679

97.2

0.444
  comE/comE1 Streptococcus equinus JB1

42.149

96.8

0.408