Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACJWMC_RS06455 Genome accession   NZ_CP177181
Coordinates   1308927..1310711 (-) Length   594 a.a.
NCBI ID   WP_002891205.1    Uniprot ID   J7TIN9
Organism   Streptococcus salivarius strain MRD1919     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1303927..1315711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS06435 cls 1304095..1305645 (-) 1551 WP_193383675.1 cardiolipin synthase -
  ACJWMC_RS06440 - 1306238..1307788 (+) 1551 WP_037597927.1 BCCT family transporter -
  ACJWMC_RS06445 - 1308039..1308362 (+) 324 WP_003096828.1 potassium channel family protein -
  ACJWMC_RS06450 - 1308333..1308614 (-) 282 WP_002891204.1 protein rep -
  ACJWMC_RS06455 uvrC 1308927..1310711 (-) 1785 WP_002891205.1 excinuclease ABC subunit UvrC Machinery gene
  ACJWMC_RS06460 - 1310783..1311478 (-) 696 WP_002891206.1 YjjG family noncanonical pyrimidine nucleotidase -
  ACJWMC_RS06465 sdaAB 1311757..1312428 (+) 672 WP_002891207.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  ACJWMC_RS06470 sdaAA 1312441..1313310 (+) 870 WP_002891209.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68585.92 Da        Isoelectric Point: 9.2203

>NTDB_id=969720 ACJWMC_RS06455 WP_002891205.1 1308927..1310711(-) (uvrC) [Streptococcus salivarius strain MRD1919]
MNDLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDDKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLQVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKHFK
SMTAIQKATVEDIQALGIPEKVAEALLDKLNDNN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=969720 ACJWMC_RS06455 WP_002891205.1 1308927..1310711(-) (uvrC) [Streptococcus salivarius strain MRD1919]
ATGAATGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAATCCTGGGTGCTATCTCCACAAGGACAAATTCGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGCTTTTGGTATCTGAGATTGCAGATTTTGAATTTATCGTAACCGAGTCCAATATTGAGGCCCTGCTTTTGGAGATTAAT
CTTATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGACAAGTCTTATCCATTTATCAAGATTACTAAGGA
GCTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGCGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CGGCCAATGAAATCAAGAAACTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCCGCCAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCATACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAATCAGCTTAAGGCCAAGATGAAGGATATGTCTGACCAGATGG
AGTTTGAGCGTGCTGCGGAGTATCGTGATTTGATTGAGGCAGTATCGACGCTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAGGTTTTCTTTGTTCGCCAAGG
AAAACTCATTCAGCGTGATGTCAATATGTTCCCTTATTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAGT
TTTATCTGGATAGTCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGAGACATTGATCAAGAGTCTGTCGAAGCTCTA
GTTGGAGATGAGGTCAAGGTCTTTAAACCTCAACGTGGCGAGAAGAAGCAGTTGGTTAATCTGGCGACGAAAAATGCCCG
TGTCAGTCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCCGCCATG
GTCGTCTTTGAGAATGGAAAACCCAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGACGTTATAGTCGTGTCAAACGCGATGGGCTAACACCACCAGATCTTATTATCA
TGGATGGTGGTCAAGGACAGGTCAATGTGGCCAAGGATGTCCTACGCAATGAATTGAATCTTTCTATCCCAGTTGCGGGG
CTTCAGAAAAATGACAAGCACCAAACCAACGAATTGCTCTTTGGGGACCCCTTGCAGGTCATTGATTTGCCACGGCAATC
CGAGGAATTTTTCCTTCTTCACCGTATCCAAGATGAAGTTCACCGTTTTGCTATCACCTTCCACCGTCAAGTTCGTAGTA
AAAATAGTTTCAGCTCCAAACTTGATGGCGTGGAGGGCCTTGGACCTAAGCGCAAACAAAAACTTCTCAAACACTTCAAG
TCTATGACAGCTATCCAAAAAGCTACTGTTGAGGACATCCAAGCACTTGGCATTCCAGAAAAAGTAGCAGAGGCTCTGTT
AGATAAATTAAATGATAACAATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(540-592)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TIN9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.65

99.495

0.763
  uvrC Streptococcus pneumoniae R6

76.311

99.495

0.759
  uvrC Streptococcus pneumoniae D39

76.311

99.495

0.759