Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACJVC4_RS07330 Genome accession   NZ_CP177179
Coordinates   1598044..1598688 (-) Length   214 a.a.
NCBI ID   WP_002891417.1    Uniprot ID   J7TMS3
Organism   Streptococcus salivarius strain MRD-NRLLH     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1593044..1603688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVC4_RS07305 - 1595122..1596120 (-) 999 WP_002891413.1 NAD(P)/FAD-dependent oxidoreductase -
  ACJVC4_RS07310 trmD 1596122..1596841 (-) 720 WP_002891414.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  ACJVC4_RS07315 rimM 1596831..1597349 (-) 519 WP_002891416.1 ribosome maturation factor RimM -
  ACJVC4_RS07330 vraR 1598044..1598688 (-) 645 WP_002891417.1 response regulator transcription factor Regulator
  ACJVC4_RS07335 - 1598678..1599688 (-) 1011 WP_002891418.1 sensor histidine kinase -
  ACJVC4_RS07340 liaF 1599685..1600383 (-) 699 WP_002891419.1 cell wall-active antibiotics response protein LiaF -
  ACJVC4_RS07345 - 1600546..1601304 (-) 759 WP_037598279.1 potassium channel family protein -
  ACJVC4_RS07350 stkP/pknB 1601449..1603323 (-) 1875 WP_002891421.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24007.33 Da        Isoelectric Point: 4.5814

>NTDB_id=969486 ACJVC4_RS07330 WP_002891417.1 1598044..1598688(-) (vraR) [Streptococcus salivarius strain MRD-NRLLH]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEASNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=969486 ACJVC4_RS07330 WP_002891417.1 1598044..1598688(-) (vraR) [Streptococcus salivarius strain MRD-NRLLH]
ATGTCGAATAAGATAAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGCCTTAAGAGTTTCCTGAATCTCCA
AGGAGATGTCGAAGTGGTTGGAGAAGCGAGCAATGGCCGAGAAGGTGTTGACCTTGCCCTGGAACTTCGTCCAGATGTCG
TCGTAATGGACCTTGTCATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCAGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGTGCTAAAGGTTATATGCTTAA
AACTAGCAGTGCAGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACAGAGGTGGACA
ATAAGATTAAATACCATGATAGCCATCCGGACCTACACGATGACTTAACGGCACGTGAACGTGATATCCTGGCGCTTTTG
GCTAAGGGTTATGACAATCAGACCATTGCTAACGAGCTATTCATTTCATTGAAAACAGTTAAAACTCACGTGTCTAATAT
CCTAGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTCGTTTATGCCTTTAGACATCATTTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7TMS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379