Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACK3BL_RS09650 Genome accession   NZ_CP176786
Coordinates   1955278..1955934 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain XJ23PTE1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1950278..1960934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK3BL_RS09615 dcyD 1951157..1952143 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACK3BL_RS09620 tcyL 1952158..1952826 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACK3BL_RS09625 tcyN 1952823..1953575 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACK3BL_RS09630 sdiA 1953805..1954527 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  ACK3BL_RS09635 yecF 1954595..1954819 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACK3BL_RS09640 yecU 1954806..1954982 (-) 177 WP_000590344.1 protein YecU -
  ACK3BL_RS09645 - 1955020..1955136 (-) 117 WP_001302039.1 hypothetical protein -
  ACK3BL_RS09650 letA 1955278..1955934 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACK3BL_RS09655 uvrC 1955931..1957763 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACK3BL_RS09660 pgsA 1957820..1958368 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACK3BL_RS09680 yecA 1959017..1959682 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=968926 ACK3BL_RS09650 WP_000611328.1 1955278..1955934(+) (letA) [Escherichia coli strain XJ23PTE1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=968926 ACK3BL_RS09650 WP_000611328.1 1955278..1955934(+) (letA) [Escherichia coli strain XJ23PTE1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment