Detailed information NTG0968180

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MKX71_RS18235
• Genome accession: NZ_CP150256
• Coordinates: 3521649..3522806 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. FSL M8-0071
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3516649..3527806

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKX71_RS18205 (MKX71_18205)	-	3516901..3517320 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
MKX71_RS18210 (MKX71_18210)	comFC	3517394..3518116 (-)	723	WP_029725992.1	comF operon protein ComFC	Machinery gene
MKX71_RS18215 (MKX71_18215)	comFB	3518080..3518376 (-)	297	WP_339231459.1	late competence protein ComFB	-
MKX71_RS18220 (MKX71_18220)	comFA	3518436..3519827 (-)	1392	WP_339231460.1	ATP-dependent helicase ComFA	Machinery gene
MKX71_RS18225 (MKX71_18225)	-	3519934..3520779 (-)	846	WP_128738295.1	DegV family protein	-
MKX71_RS18230 (MKX71_18230)	degU	3520877..3521566 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MKX71_RS18235 (MKX71_18235)	degS	3521649..3522806 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
MKX71_RS18240 (MKX71_18240)	-	3523023..3523676 (+)	654	WP_003227979.1	YigZ family protein	-
MKX71_RS18245 (MKX71_18245)	tagV	3523676..3524851 (+)	1176	WP_161476660.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
MKX71_RS18250 (MKX71_18250)	-	3524923..3525999 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
MKX71_RS18255 (MKX71_18255)	-	3526144..3527337 (-)	1194	WP_144482990.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=968180 MKX71_RS18235 WP_003227983.1 3521649..3522806(-) (degS) [Bacillus sp. FSL M8-0071]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=968180 MKX71_RS18235 WP_003227983.1 3521649..3522806(-) (degS) [Bacillus sp. FSL M8-0071]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTTGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1