Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACK2I5_RS04320 Genome accession   NZ_CP176645
Coordinates   929297..929953 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain SFAD3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 924297..934953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I5_RS04290 dcyD 925176..926162 (+) 987 WP_001128236.1 D-cysteine desulfhydrase -
  ACK2I5_RS04295 tcyL 926177..926845 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACK2I5_RS04300 tcyN 926842..927594 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACK2I5_RS04305 sdiA 927824..928546 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  ACK2I5_RS04310 yecF 928614..928838 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACK2I5_RS04315 yecU 928825..929001 (-) 177 WP_001304283.1 protein YecU -
  ACK2I5_RS04320 letA 929297..929953 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACK2I5_RS04325 uvrC 929950..931782 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACK2I5_RS04330 pgsA 931839..932387 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACK2I5_RS04350 yecA 933036..933701 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=967941 ACK2I5_RS04320 WP_000611328.1 929297..929953(+) (letA) [Escherichia coli strain SFAD3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=967941 ACK2I5_RS04320 WP_000611328.1 929297..929953(+) (letA) [Escherichia coli strain SFAD3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment