Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACKZ7S_RS05670 Genome accession   NZ_CP176565
Coordinates   1139727..1141508 (+) Length   593 a.a.
NCBI ID   WP_162636153.1    Uniprot ID   -
Organism   Staphylococcus aureus strain V0353     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1134727..1146508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKZ7S_RS05650 (ACKZ7S_05650) polX 1134846..1136558 (+) 1713 WP_162636154.1 DNA polymerase/3'-5' exonuclease PolX -
  ACKZ7S_RS05655 (ACKZ7S_05655) mutS/mutS2 1136568..1138916 (+) 2349 WP_001249293.1 endonuclease MutS2 Machinery gene
  ACKZ7S_RS05660 (ACKZ7S_05660) trxA 1139089..1139403 (+) 315 WP_001018928.1 thioredoxin -
  ACKZ7S_RS05665 (ACKZ7S_05665) - 1139466..1139561 (-) 96 WP_031844936.1 hypothetical protein -
  ACKZ7S_RS05670 (ACKZ7S_05670) uvrC 1139727..1141508 (+) 1782 WP_162636153.1 excinuclease ABC subunit UvrC Machinery gene
  ACKZ7S_RS05675 (ACKZ7S_05675) - 1141832..1142446 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  ACKZ7S_RS05680 (ACKZ7S_05680) sdhA 1142498..1144264 (+) 1767 WP_115305311.1 succinate dehydrogenase flavoprotein subunit -
  ACKZ7S_RS05685 (ACKZ7S_05685) sdhB 1144264..1145079 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  ACKZ7S_RS05690 (ACKZ7S_05690) racE 1145318..1146118 (+) 801 WP_162644404.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68683.41 Da        Isoelectric Point: 9.8089

>NTDB_id=967585 ACKZ7S_RS05670 WP_162636153.1 1139727..1141508(+) (uvrC) [Staphylococcus aureus strain V0353]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLNKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRTF
GSIKKMKEATLEDFKNIGIPENVAKNLYEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=967585 ACKZ7S_RS05670 WP_162636153.1 1139727..1141508(+) (uvrC) [Staphylococcus aureus strain V0353]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCAA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCCTTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGTTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGAATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATCCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGATGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCGGATTTAATTA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAAAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTACATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTTGCAAAGAACCT
ATATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565

Multiple sequence alignment