Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACKZ9B_RS14905 Genome accession   NZ_CP176488
Coordinates   2858504..2859160 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain N1131     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2853504..2864160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKZ9B_RS14875 (ACKZ9B_14870) yecA 2854755..2855420 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  ACKZ9B_RS14895 (ACKZ9B_14890) pgsA 2856070..2856618 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACKZ9B_RS14900 (ACKZ9B_14895) uvrC 2856675..2858507 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACKZ9B_RS14905 (ACKZ9B_14900) letA 2858504..2859160 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACKZ9B_RS14910 (ACKZ9B_14905) - 2859302..2859418 (+) 117 WP_023063716.1 hypothetical protein -
  ACKZ9B_RS14915 (ACKZ9B_14910) yecU 2859456..2859632 (+) 177 WP_000590344.1 protein YecU -
  ACKZ9B_RS14920 (ACKZ9B_14915) yecF 2859619..2859843 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACKZ9B_RS14925 (ACKZ9B_14920) sdiA 2859910..2860632 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  ACKZ9B_RS14930 (ACKZ9B_14925) tcyN 2860862..2861614 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACKZ9B_RS14935 (ACKZ9B_14930) tcyL 2861611..2862279 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACKZ9B_RS14940 (ACKZ9B_14935) dcyD 2862294..2863280 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=967117 ACKZ9B_RS14905 WP_000611328.1 2858504..2859160(-) (letA) [Escherichia coli strain N1131]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=967117 ACKZ9B_RS14905 WP_000611328.1 2858504..2859160(-) (letA) [Escherichia coli strain N1131]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482