Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKWPP_RS02785 Genome accession   NZ_CP176418
Coordinates   502205..502846 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain KKAHC02     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 497205..507846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS02760 (ACKWPP_02760) - 497506..498243 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACKWPP_RS02765 (ACKWPP_02765) pknB 498243..499901 (+) 1659 Protein_507 Stk1 family PASTA domain-containing Ser/Thr kinase -
  ACKWPP_RS02770 (ACKWPP_02770) - 500022..500237 (+) 216 Protein_508 serine/threonine protein kinase -
  ACKWPP_RS02775 (ACKWPP_02775) liaF 500561..501220 (+) 660 WP_226317727.1 cell wall-active antibiotics response protein LiaF -
  ACKWPP_RS02780 (ACKWPP_02780) - 501217..502233 (+) 1017 WP_002937028.1 sensor histidine kinase -
  ACKWPP_RS02785 (ACKWPP_02785) vraR 502205..502846 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  ACKWPP_RS02790 (ACKWPP_02790) - 502896..504296 (+) 1401 WP_044668895.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACKWPP_RS02795 (ACKWPP_02795) - 504298..504669 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  ACKWPP_RS02800 (ACKWPP_02800) cysK 504695..505621 (-) 927 WP_044668892.1 cysteine synthase A -
  ACKWPP_RS02805 (ACKWPP_02805) - 505711..506343 (-) 633 WP_015646510.1 YigZ family protein -
  ACKWPP_RS02810 (ACKWPP_02810) comFA/cflA 506400..507692 (+) 1293 WP_044668890.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=966828 ACKWPP_RS02785 WP_002937025.1 502205..502846(+) (vraR) [Streptococcus suis strain KKAHC02]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=966828 ACKWPP_RS02785 WP_002937025.1 502205..502846(+) (vraR) [Streptococcus suis strain KKAHC02]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTCCGTCTAGGATTGAAAAGTTACTTAAATTTACAACC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTGGAGGTTAAGCCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACTTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment