Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NYE79_RS08430 Genome accession   NZ_CP150168
Coordinates   1696478..1697167 (-) Length   229 a.a.
NCBI ID   WP_000518005.1    Uniprot ID   A0A1X0WQD0
Organism   Streptococcus sp. FSL W8-0197     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1691478..1702167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS08410 (NYE79_08410) mvaD 1692400..1693353 (-) 954 WP_213952276.1 diphosphomevalonate decarboxylase -
  NYE79_RS08415 (NYE79_08415) mvk 1693335..1694213 (-) 879 WP_000163295.1 mevalonate kinase -
  NYE79_RS08420 (NYE79_08420) cbpC 1694331..1695350 (-) 1020 WP_000771069.1 choline-binding protein CbpC -
  NYE79_RS08425 (NYE79_08425) cbpJ 1695368..1696378 (-) 1011 WP_216728551.1 choline-binding protein CbpJ -
  NYE79_RS08430 (NYE79_08430) covR 1696478..1697167 (-) 690 WP_000518005.1 response regulator transcription factor Regulator
  NYE79_RS08435 (NYE79_08435) gndA 1697179..1698603 (-) 1425 WP_000158772.1 NADP-dependent phosphogluconate dehydrogenase -
  NYE79_RS08440 (NYE79_08440) - 1698679..1700124 (-) 1446 WP_217970543.1 cell division site-positioning protein MapZ family protein -
  NYE79_RS08445 (NYE79_08445) - 1700137..1701294 (-) 1158 WP_217970542.1 class I SAM-dependent RNA methyltransferase -
  NYE79_RS08455 (NYE79_08455) gpsB 1701780..1702109 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26827.00 Da        Isoelectric Point: 8.0271

>NTDB_id=964625 NYE79_RS08430 WP_000518005.1 1696478..1697167(-) (covR) [Streptococcus sp. FSL W8-0197]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=964625 NYE79_RS08430 WP_000518005.1 1696478..1697167(-) (covR) [Streptococcus sp. FSL W8-0197]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACATTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X0WQD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment