Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACI77Q_RS12660 Genome accession   NZ_CP174267
Coordinates   2556607..2558439 (-) Length   610 a.a.
NCBI ID   WP_001283395.1    Uniprot ID   -
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12 isolate original strain     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2551607..2563439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI77Q_RS12615 (ACI77Q_12615) yecR 2551955..2552278 (+) 324 WP_001237869.1 YecR-like lipofamily protein -
  ACI77Q_RS12620 (ACI77Q_12620) ftnA 2552449..2552946 (+) 498 WP_000917208.1 non-heme ferritin -
  ACI77Q_RS12625 (ACI77Q_12625) yecH 2552984..2553223 (-) 240 WP_000377225.1 YecH family metal-binding protein -
  ACI77Q_RS12630 (ACI77Q_12630) tyrP 2553414..2554625 (+) 1212 WP_000797560.1 tyrosine transporter TyrP -
  ACI77Q_RS12635 (ACI77Q_12635) yecA 2554687..2555352 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ACI77Q_RS12655 (ACI77Q_12655) pgsA 2556002..2556550 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI77Q_RS12660 (ACI77Q_12660) uvrC 2556607..2558439 (-) 1833 WP_001283395.1 excinuclease ABC subunit UvrC Machinery gene
  ACI77Q_RS12665 (ACI77Q_12665) letA 2558436..2559092 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACI77Q_RS12670 (ACI77Q_12670) - 2559234..2559305 (+) 72 Protein_2466 transcriptional regulator -
  ACI77Q_RS12675 (ACI77Q_12675) yecU 2559388..2559564 (+) 177 WP_000590347.1 protein YecU -
  ACI77Q_RS12680 (ACI77Q_12680) yecF 2559551..2559775 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACI77Q_RS12685 (ACI77Q_12685) sdiA 2559843..2560565 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  ACI77Q_RS12690 (ACI77Q_12690) tcyN 2560795..2561547 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACI77Q_RS12695 (ACI77Q_12695) tcyL 2561544..2562212 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACI77Q_RS12700 (ACI77Q_12700) dcyD 2562227..2563213 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68162.00 Da        Isoelectric Point: 9.3824

>NTDB_id=964612 ACI77Q_RS12660 WP_001283395.1 2556607..2558439(-) (uvrC) [Escherichia coli str. K-12 substr. MG1655 strain K-12 isolate original strain]
MSDQFDAKAFLKTVTSQPGVYRMHDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=964612 ACI77Q_RS12660 WP_001283395.1 2556607..2558439(-) (uvrC) [Escherichia coli str. K-12 substr. MG1655 strain K-12 isolate original strain]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGCACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATACCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGACTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCACCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374

Multiple sequence alignment