Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NYE79_RS03315 Genome accession   NZ_CP150168
Coordinates   640739..641971 (+) Length   410 a.a.
NCBI ID   WP_002874765.1    Uniprot ID   A0A1X1GRP7
Organism   Streptococcus sp. FSL W8-0197     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 636411..648609 640739..641971 within 0


Gene organization within MGE regions


Location: 636411..648609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS03280 (NYE79_03280) galE 636411..637430 (+) 1020 WP_001156532.1 UDP-glucose 4-epimerase GalE -
  NYE79_RS03285 (NYE79_03285) - 637432..638397 (+) 966 WP_216728766.1 glycosyltransferase family 2 protein -
  NYE79_RS03290 (NYE79_03290) - 638473..638676 (-) 204 WP_004246691.1 ferredoxin -
  NYE79_RS03295 (NYE79_03295) - 638722..639228 (+) 507 WP_216728706.1 SAG1386/EF1546 family surface-associated protein -
  NYE79_RS03300 (NYE79_03300) cmk 639238..639912 (+) 675 WP_000849409.1 (d)CMP kinase -
  NYE79_RS03305 (NYE79_03305) - 640031..640537 (+) 507 WP_042902706.1 dihydrofolate reductase -
  NYE79_RS03310 (NYE79_03310) - 640537..640707 (+) 171 WP_000442252.1 hypothetical protein -
  NYE79_RS03315 (NYE79_03315) clpX 640739..641971 (+) 1233 WP_002874765.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NYE79_RS03320 (NYE79_03320) yihA 641980..642567 (+) 588 WP_000405203.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NYE79_RS03325 (NYE79_03325) - 642577..642957 (+) 381 WP_001140420.1 RidA family protein -
  NYE79_RS03330 (NYE79_03330) rapZ 643009..643899 (+) 891 WP_216728705.1 RNase adapter RapZ -
  NYE79_RS03335 (NYE79_03335) - 643896..644873 (+) 978 WP_057489476.1 YvcK family protein -
  NYE79_RS03340 (NYE79_03340) whiA 644870..645781 (+) 912 WP_216728704.1 DNA-binding protein WhiA -
  NYE79_RS03345 (NYE79_03345) - 645869..646462 (-) 594 WP_251463669.1 site-specific integrase -
  NYE79_RS03350 (NYE79_03350) - 646450..646995 (-) 546 WP_268702962.1 hypothetical protein -
  NYE79_RS03355 (NYE79_03355) - 647242..648012 (-) 771 WP_216728703.1 type II toxin-antitoxin system PemK/MazF family toxin -
  NYE79_RS03360 (NYE79_03360) - 648094..648609 (-) 516 WP_216728702.1 hypothetical protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45686.26 Da        Isoelectric Point: 4.4581

>NTDB_id=964602 NYE79_RS03315 WP_002874765.1 640739..641971(+) (clpX) [Streptococcus sp. FSL W8-0197]
MPTNRKNDMMVYCSFCGKSQEEVKKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTEKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=964602 NYE79_RS03315 WP_002874765.1 640739..641971(+) (clpX) [Streptococcus sp. FSL W8-0197]
ATGCCTACAAATAGGAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTAAAGAAAATAAT
CGCTGGGAACAACGCTTTTATCTGTAATGAATGTGTTGAGTTGGCCCAGGAAATCATTCGGGAGGAGTTGGCCGAGGAAG
TTTTGGCAGACTTGTCTGAAGTACCAAAACCAATCGAACTCCTCAATATTCTAAACCACTATGTGATTGGTCAGGATCGT
GCCAAACGTGCCTTGGCAGTGGCTGTATACAATCACTATAAACGTATCAATTTTCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGTCCAACTGGTTCAGGAAAAACTTTCTTGGCTCAGACTTTGGCTA
AGAGCTTGAACGTGCCTTTTGCTATTGCAGATGCGACAGCTCTGACTGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGCTGCTGACTTTAACATCGAACGTGCAGAACGTGGGATTATCTACGTAGATGAAATTGA
CAAAATTGCCAAGAAGAGCGAGAATGTGTCTATCACACGTGACGTTTCGGGTGAAGGTGTGCAACAAGCCCTTCTCAAGA
TTATTGAGGGAACTGTTGCTAGCGTGCCACCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAGGTGGATACC
AAGAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGCATCGAAGAAATCGTCAAACAACGTCTGGGAGAAAAAGTCAT
TGGTTTTGGCCAAAATAACAAGGCGATTGACGAAAACAGCTCCTACATGCAAGAAATCATCGCAGAAGACATTCAAAAAT
TCGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTCTTTGCTGCTCTTGAGCAATTGACGGTCGATGACTTGGTTCGC
ATCTTGAAGGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
TGATGAAGCCCTTCAGGAAATCGCCAATAAGGCTATCGAACGCAAGACAGGTGCGCGTGGTCTTCGCTCAATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAAGTGCCAAGTCAGGAAAATGTGAAATTGGTCCGCATCACGAAAGAAGCTGTCGAT
GGAACGGAAAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GRP7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.073

100

0.871
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment