Detailed information NTG0964044

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACJEHH_RS00375
• Genome accession: NZ_CP174238
• Coordinates: 78771..80045 (+)
• Length: 424 a.a.
• NCBI ID: WP_011215825.1
• Uniprot ID: Q5WVJ1
• Organism: Legionella pneumophila strain SPF587
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 73771..85045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEHH_RS00340 (ACJEHH_00340)	-	74564..75790 (-)	1227	WP_011215830.1	site-specific integrase	-
ACJEHH_RS00365 (ACJEHH_00365)	tig	76652..77983 (+)	1332	WP_011215827.1	trigger factor	-
ACJEHH_RS00370 (ACJEHH_00370)	clpP	77986..78630 (+)	645	WP_011215826.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACJEHH_RS00375 (ACJEHH_00375)	clpX	78771..80045 (+)	1275	WP_011215825.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACJEHH_RS00380 (ACJEHH_00380)	lon	80279..82729 (+)	2451	WP_011215824.1	endopeptidase La	-
ACJEHH_RS00385 (ACJEHH_00385)	-	82858..83136 (+)	279	WP_011214112.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46641.21 Da
• Isoelectric Point: 5.0727

>NTDB_id=964044 ACJEHH_RS00375 WP_011215825.1 78771..80045(+) (clpX) [Legionella pneumophila strain SPF587]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=964044 ACJEHH_RS00375 WP_011215825.1 78771..80045(+) (clpX) [Legionella pneumophila strain SPF587]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGTTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTATGTAATGATATTATTCGAGAAGAAACACATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
ACTTGGTAAAAGTAATATACTTCTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACTCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGTGAAGACGTTGAAAATATCATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAAGAATTTTTGCAAGTAGATACGTCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAGCGGAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGGCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTAATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCGAAGAATGCTTTAACAAAGCAGTTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTCGA
GTTTAGAGACGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACCATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGGCTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5WVJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526