Detailed information NTG0963846

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACJEH2_RS01185
• Genome accession: NZ_CP174235
• Coordinates: 277645..278919 (-)
• Length: 424 a.a.
• NCBI ID: WP_011215825.1
• Uniprot ID: Q5WVJ1
• Organism: Legionella pneumophila strain SPF590
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 272645..283919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEH2_RS01175 (ACJEH2_01175)	-	274554..274832 (-)	279	WP_011214112.1	HU family DNA-binding protein	-
ACJEH2_RS01180 (ACJEH2_01180)	lon	274961..277411 (-)	2451	WP_011215824.1	endopeptidase La	-
ACJEH2_RS01185 (ACJEH2_01185)	clpX	277645..278919 (-)	1275	WP_011215825.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACJEH2_RS01190 (ACJEH2_01190)	clpP	279060..279704 (-)	645	WP_011215826.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACJEH2_RS01195 (ACJEH2_01195)	tig	279707..281038 (-)	1332	WP_011215827.1	trigger factor	-
ACJEH2_RS01220 (ACJEH2_01220)	-	281900..283126 (+)	1227	WP_011215830.1	site-specific integrase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46641.21 Da
• Isoelectric Point: 5.0727

>NTDB_id=963846 ACJEH2_RS01185 WP_011215825.1 277645..278919(-) (clpX) [Legionella pneumophila strain SPF590]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=963846 ACJEH2_RS01185 WP_011215825.1 277645..278919(-) (clpX) [Legionella pneumophila strain SPF590]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGTTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTATGTAATGATATTATTCGAGAAGAAACACATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
ACTTGGTAAAAGTAATATACTTCTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACTCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGTGAAGACGTTGAAAATATCATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAAGAATTTTTGCAAGTAGATACGTCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAGCGGAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGGCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTAATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCGAAGAATGCTTTAACAAAGCAGTTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTCGA
GTTTAGAGACGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACCATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGGCTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5WVJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526