Detailed information NTG0963572

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACJEH0_RS01250
• Genome accession: NZ_CP174231
• Coordinates: 258370..259644 (+)
• Length: 424 a.a.
• NCBI ID: WP_015444406.1
• Uniprot ID: Q5ZUE0
• Organism: Legionella pneumophila strain SPF633
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 253370..264644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEH0_RS01215 (ACJEH0_01215)	-	254163..255389 (-)	1227	WP_010947587.1	site-specific integrase	-
ACJEH0_RS01240 (ACJEH0_01240)	tig	256251..257582 (+)	1332	WP_010947586.1	trigger factor	-
ACJEH0_RS01245 (ACJEH0_01245)	clpP	257585..258229 (+)	645	WP_010947585.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACJEH0_RS01250 (ACJEH0_01250)	clpX	258370..259644 (+)	1275	WP_015444406.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACJEH0_RS01255 (ACJEH0_01255)	lon	259882..262332 (+)	2451	WP_010947583.1	endopeptidase La	-
ACJEH0_RS01260 (ACJEH0_01260)	-	262461..262739 (+)	279	WP_011214112.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46583.17 Da
• Isoelectric Point: 5.1603

>NTDB_id=963572 ACJEH0_RS01250 WP_015444406.1 258370..259644(+) (clpX) [Legionella pneumophila strain SPF633]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=963572 ACJEH0_RS01250 WP_015444406.1 258370..259644(+) (clpX) [Legionella pneumophila strain SPF633]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTTTGTAATGATATTATTCGAGAAGAGACGCATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
GCTCGGCAAAAGTAATATTTTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGCGAAGACGTTGAAAATATTATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAGGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTGATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCTAAGAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGGCGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACTATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5ZUE0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526