Detailed information NTG0963360

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACJEHG_RS00365
• Genome accession: NZ_CP174228
• Coordinates: 72255..73529 (+)
• Length: 424 a.a.
• NCBI ID: WP_015444406.1
• Uniprot ID: Q5ZUE0
• Organism: Legionella pneumophila strain SPF638
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 67255..78529

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEHG_RS00330 (ACJEHG_00330)	-	68048..69274 (-)	1227	WP_010947587.1	site-specific integrase	-
ACJEHG_RS00355 (ACJEHG_00355)	tig	70136..71467 (+)	1332	WP_010947586.1	trigger factor	-
ACJEHG_RS00360 (ACJEHG_00360)	clpP	71470..72114 (+)	645	WP_010947585.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACJEHG_RS00365 (ACJEHG_00365)	clpX	72255..73529 (+)	1275	WP_015444406.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACJEHG_RS00370 (ACJEHG_00370)	lon	73767..76217 (+)	2451	WP_010947583.1	endopeptidase La	-
ACJEHG_RS00375 (ACJEHG_00375)	-	76346..76624 (+)	279	WP_011214112.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46583.17 Da
• Isoelectric Point: 5.1603

>NTDB_id=963360 ACJEHG_RS00365 WP_015444406.1 72255..73529(+) (clpX) [Legionella pneumophila strain SPF638]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=963360 ACJEHG_RS00365 WP_015444406.1 72255..73529(+) (clpX) [Legionella pneumophila strain SPF638]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTTTGTAATGATATTATTCGAGAAGAGACGCATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
GCTCGGCAAAAGTAATATTTTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGCGAAGACGTTGAAAATATTATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAGGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTGATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCTAAGAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGGCGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACTATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5ZUE0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526