Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   OW489_RS07925 Genome accession   NZ_AP026446
Coordinates   1649495..1650697 (+) Length   400 a.a.
NCBI ID   WP_120856471.1    Uniprot ID   -
Organism   Helicobacter pylori strain CHC155     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1631899..1689492 1649495..1650697 within 0


Gene organization within MGE regions


Location: 1631899..1689492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OW489_RS07830 (CHC155_15300) - 1632210..1633217 (+) 1008 WP_267285997.1 ferrochelatase -
  OW489_RS07835 (CHC155_15310) cmoB 1633221..1634006 (+) 786 WP_120857421.1 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB -
  OW489_RS07840 (CHC155_15320) - 1634023..1634451 (+) 429 WP_001158247.1 hotdog domain-containing protein -
  OW489_RS07845 (CHC155_15330) - 1634456..1635625 (+) 1170 WP_267285998.1 glycosyltransferase family 4 protein -
  OW489_RS07850 (CHC155_15340) speA 1635640..1637487 (+) 1848 WP_001158557.1 arginine decarboxylase -
  OW489_RS07855 (CHC155_15350) - 1637609..1638484 (-) 876 WP_120857427.1 hypothetical protein -
  OW489_RS08160 - 1638589..1640436 (-) 1848 Protein_1541 hypothetical protein -
  OW489_RS07875 (CHC155_15390) - 1640481..1641646 (-) 1166 Protein_1542 DHH family protein -
  OW489_RS07880 (CHC155_15410) - 1641777..1642565 (+) 789 WP_120856481.1 integrase -
  OW489_RS07885 (CHC155_15420) - 1642669..1643148 (+) 480 WP_162966579.1 hypothetical protein -
  OW489_RS07890 (CHC155_15430) comB2 1643145..1643429 (+) 285 WP_000736478.1 TrbC/VirB2 family protein Machinery gene
  OW489_RS07895 (CHC155_15440) comB3 1643440..1643703 (+) 264 WP_001177712.1 hypothetical protein Machinery gene
  OW489_RS07900 (CHC155_15450) - 1643714..1643950 (+) 237 WP_120824245.1 hypothetical protein -
  OW489_RS07905 (CHC155_15460) - 1643950..1646532 (+) 2583 WP_120856479.1 VirB4 family type IV secretion/conjugal transfer ATPase -
  OW489_RS07910 - 1646529..1646663 (+) 135 WP_120856477.1 type IV secretion system protein VirB7 -
  OW489_RS07915 (CHC155_15470) - 1646656..1647825 (+) 1170 WP_120856475.1 VirB8/TrbF family protein -
  OW489_RS07920 (CHC155_15480) - 1647822..1649498 (+) 1677 WP_120856473.1 TrbG/VirB9 family P-type conjugative transfer protein -
  OW489_RS07925 (CHC155_15490) comB10 1649495..1650697 (+) 1203 WP_120856471.1 DNA type IV secretion system protein ComB10 Machinery gene
  OW489_RS07930 (CHC155_15500) - 1650681..1652930 (+) 2250 WP_120856469.1 collagen-like protein -
  OW489_RS07935 (CHC155_15510) - 1652943..1653920 (+) 978 WP_120824239.1 hypothetical protein -
  OW489_RS07940 (CHC155_15520) - 1653938..1654210 (+) 273 WP_205583491.1 hypothetical protein -
  OW489_RS07945 (CHC155_15530) - 1654215..1655159 (+) 945 WP_120824237.1 CpaF/VirB11 family protein -
  OW489_RS07950 (CHC155_15540) - 1655156..1655674 (+) 519 WP_120824236.1 replication regulatory RepB family protein -
  OW489_RS07955 (CHC155_15550) - 1655671..1657935 (+) 2265 WP_120824235.1 type IV secretory system conjugative DNA transfer family protein -
  OW489_RS07960 (CHC155_15560) - 1657955..1666555 (+) 8601 WP_120856467.1 SNF2-related protein -
  OW489_RS07965 (CHC155_15570) - 1666890..1668950 (+) 2061 WP_120856465.1 type IA DNA topoisomerase -
  OW489_RS07970 (CHC155_15580) - 1669005..1669475 (+) 471 WP_000965788.1 hypothetical protein -
  OW489_RS07975 - 1669445..1670235 (+) 791 Protein_1562 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  OW489_RS07980 (CHC155_15610) - 1670357..1670929 (-) 573 WP_120856463.1 hypothetical protein -
  OW489_RS07985 (CHC155_15620) - 1670907..1671284 (-) 378 WP_120856461.1 hypothetical protein -
  OW489_RS07990 (CHC155_15630) - 1671346..1671996 (-) 651 WP_120824227.1 ParA family protein -
  OW489_RS07995 (CHC155_15640) - 1672634..1672798 (+) 165 WP_015427674.1 hypothetical protein -
  OW489_RS08000 (CHC155_15650) - 1672799..1673866 (+) 1068 WP_120824226.1 ArdC family protein -
  OW489_RS08005 (CHC155_15660) - 1673866..1675872 (+) 2007 WP_120928866.1 hypothetical protein -
  OW489_RS08010 (CHC155_15670) - 1675882..1677315 (+) 1434 WP_267286001.1 hypothetical protein -
  OW489_RS08015 (CHC155_15680) - 1677312..1678562 (+) 1251 WP_267286002.1 P-type conjugative transfer protein TrbL -
  OW489_RS08020 (CHC155_15690) - 1678559..1679815 (+) 1257 WP_267286003.1 hypothetical protein -
  OW489_RS08025 (CHC155_15700) - 1679837..1680565 (-) 729 WP_120858363.1 hypothetical protein -
  OW489_RS08030 (CHC155_15710) ctkA 1680794..1681771 (+) 978 WP_120858365.1 serine/threonine-protein kinase CtkA -
  OW489_RS08035 (CHC155_15720) - 1682089..1683156 (-) 1068 WP_120824220.1 tyrosine-type recombinase/integrase -
  OW489_RS08040 (CHC155_15730) - 1684232..1686232 (-) 2001 WP_205583492.1 relaxase/mobilization nuclease domain-containing protein -
  OW489_RS08045 (CHC155_15740) - 1687149..1688225 (-) 1077 Protein_1576 HsdR family type I site-specific deoxyribonuclease -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 44721.38 Da        Isoelectric Point: 9.8768

>NTDB_id=96324 OW489_RS07925 WP_120856471.1 1649495..1650697(+) (comB10) [Helicobacter pylori strain CHC155]
MKQSLLKKIGLVIGGFGALMALGLLANKGSNNNNKEEIYSIEESKFPLSDYFFEEVKEEPKKEENPKTITTPQPAAPTTA
NVSTNPIITDYSHLNSNLNKQNDTITHLQQVLQSPPKMKPKLKYTKEQLEFLNTRLKPLEPTKPATKPETEYGVDSFSNL
RYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRLNIA
WTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANQQNKKGDGNPFFGDYLL
MQLTRNTGMGINQVINQMLRQYGAQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKKSDEEVNNEEEI

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=96324 OW489_RS07925 WP_120856471.1 1649495..1650697(+) (comB10) [Helicobacter pylori strain CHC155]
ATGAAACAATCCTTACTTAAAAAAATCGGCTTAGTTATAGGGGGATTTGGTGCTTTAATGGCATTAGGATTGCTTGCTAA
TAAAGGTTCTAACAATAACAATAAAGAAGAAATTTACAGCATAGAAGAAAGTAAATTTCCCTTAAGCGATTATTTCTTTG
AAGAAGTCAAAGAAGAACCAAAAAAAGAAGAAAACCCCAAAACAATAACTACGCCACAACCTGCAGCTCCAACTACTGCC
AATGTTTCAACTAATCCTATCATTACAGATTATAGTCATCTTAACAGCAATCTCAACAAGCAAAATGACACCATCACGCA
TTTGCAACAAGTTTTACAAAGCCCCCCTAAAATGAAACCTAAATTAAAGTATACTAAAGAGCAATTAGAGTTTTTAAACA
CACGCCTTAAACCTTTAGAACCAACTAAACCAGCCACTAAGCCTGAGACGGAATATGGCGTGGATAGTTTTAGCAATTTA
AGATATAAAGACATCGGCACTAATGAGCATAAGCTCTTAAGAACTATAACCGCTGATAGAATGATACCAGCCTTTTTAAT
CACGCCTATTAGTTCTCAAATCGCTGGAAAAGTAACCGCTCAAGTAGAGAGCGATATTTTTGCTTCTATGGGTAGAGCGG
TGCTAATTCCTAAAGGCTCTAAAGTTATAGGCTATTACAATAACAATAATCAAATCGGGCAATACCGCTTAAACATTGCT
TGGACTAGAATTATCACCCCTCAAGGCATAAATATCATGCTCACTAATGCAAGGGGGGCTGATGTGAAAGGCTATAACGG
CTTAGTAGGCAAATATATTAGCCGAAATTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTTTCTAATGGGCTTT
TAATAGGAATTACTTCAGCCTTAGCTAATCAACAAAATAAAAAAGGTGATGGCAACCCTTTTTTTGGGGATTACTTGCTT
ATGCAACTCACTAGAAACACAGGCATGGGGATTAACCAAGTTATCAATCAAATGCTAAGACAATATGGAGCGCAAAACCC
CATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGTCCTAATTTAGACATCTTTATCCCTAAACCAAAAGATGGGG
AGGTTCTAGCGGAGTTTTTTAAAGAGAAAAAACCACTAATCAAAAAATCAGACGAGGAAGTTAATAATGAAGAAGAAATC
TAA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(175-365)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

53.181

98.25

0.523

Multiple sequence alignment