Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACI5E1_RS06705 Genome accession   NZ_CP173662
Coordinates   1479609..1480868 (-) Length   419 a.a.
NCBI ID   WP_005598324.1    Uniprot ID   A0ABM6X5K8
Organism   Actinobacillus pleuropneumoniae strain APL2305174E     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1474609..1485868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI5E1_RS06675 (ACI5E1_06665) gltX 1475922..1477361 (+) 1440 WP_237592596.1 glutamate--tRNA ligase -
  ACI5E1_RS06685 (ACI5E1_06675) yefM 1477699..1477950 (+) 252 WP_017357689.1 YoeB-YefM toxin-antitoxin system antitoxin YefM -
  ACI5E1_RS06690 (ACI5E1_06680) - 1477947..1478207 (+) 261 WP_237593298.1 Txe/YoeB family addiction module toxin -
  ACI5E1_RS06695 (ACI5E1_06685) - 1478366..1478533 (-) 168 WP_005598320.1 Trm112 family protein -
  ACI5E1_RS06700 (ACI5E1_06690) lpxK 1478535..1479515 (-) 981 WP_005608502.1 tetraacyldisaccharide 4'-kinase -
  ACI5E1_RS06705 (ACI5E1_06695) clpX 1479609..1480868 (-) 1260 WP_005598324.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  ACI5E1_RS06710 (ACI5E1_06700) clpP 1480868..1481458 (-) 591 WP_005598326.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
  ACI5E1_RS06715 (ACI5E1_06705) - 1481580..1481972 (+) 393 WP_005620423.1 SufE family protein -
  ACI5E1_RS06730 (ACI5E1_06720) dnaQ 1482331..1483104 (-) 774 WP_237593300.1 DNA polymerase III subunit epsilon -
  ACI5E1_RS06735 (ACI5E1_06725) ettA 1483191..1484861 (-) 1671 WP_237593301.1 energy-dependent translational throttle protein EttA -
  ACI5E1_RS06740 (ACI5E1_06730) - 1485026..1485364 (+) 339 WP_237593302.1 carboxymuconolactone decarboxylase family protein -
  ACI5E1_RS06745 (ACI5E1_06735) - 1485357..1485725 (+) 369 WP_005598332.1 rhodanese-like domain-containing protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 46361.06 Da        Isoelectric Point: 5.1999

>NTDB_id=961637 ACI5E1_RS06705 WP_005598324.1 1479609..1480868(-) (clpX) [Actinobacillus pleuropneumoniae strain APL2305174E]
MANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKFFENVPTPHEINAHLDEYVIG
QEHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNILLIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGE
DVENVIQKLLMKCDFDAEQAERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETI
PVDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLVKFGLIPELIGRLPVVTPLQE
LDEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALIAIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNV
KKVTVGKGCVENGDKPKVE

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=961637 ACI5E1_RS06705 WP_005598324.1 1479609..1480868(-) (clpX) [Actinobacillus pleuropneumoniae strain APL2305174E]
ATGGCAAATTTCGAGAAAGAACCGCATTGTAGTTTTTGTGGTAAAAGACGTACCGAAGTTGATCAACTGGTAGAAGGTAC
GGAAGGTTATATCTGTAATCACTGTATTGAAGAGTCTTACGCATTGTTAAACGGCGAAGAAGAACCGTTAATCGATGAAA
AACAGGATGAACAGAAGTTTTTTGAAAATGTGCCGACGCCACACGAGATCAATGCGCATTTAGATGAGTATGTTATCGGT
CAAGAGCATGCGAAAAAAGTGTTGTCCGTAGCGGTTTATAACCACTATAAACGTTTACGTAACGCGCTTTCCGGTCATAA
AGAAACCAACGGCGTAGAGTTGGGTAAAAGTAACATTTTATTAATCGGCCCGACCGGTAGCGGTAAAACCTTATTGGCGG
AAACGTTAGCGCGCCGTTTAAACGTACCCTTTGCGGTTGCGGATGCAACCACGCTGACGCAAGCCGGTTATGTCGGTGAA
GACGTAGAAAACGTGATTCAAAAATTACTGATGAAATGTGATTTTGATGCGGAACAAGCGGAACGCGGTATCGTCTTTAT
TGATGAGATTGACAAAATCACCCGTAAGTCGGAAAGCCCGTCGATTACCCGCGATGTATCCGGTGAAGGCGTGCAACAGG
CGTTATTAAAATTAATCGAAGGCACGGTAGCGAATATCAATCCGCAAGGCAGCCGTAAACACCCGAAAGGCGAAACGATT
CCGGTCGATACCTCTAAAATCCTCTTTATTTGCGGCGGAGCGTTTGCCGGTTTAGATAAGATTGTCGAGGCTCGTAGTAA
CAAGCAAGGCGGAATCGGTTTTGGCGCAGAATTGAAAAAAGATAAAGAACGTGAAGATCTCACCGAGTTATTCAAACAAG
TTGAGCCGGAAGACTTGGTTAAATTCGGTTTAATTCCGGAGCTTATCGGTCGATTACCGGTTGTGACTCCGTTACAAGAA
CTGGATGAAGAAGCGTTAATTCAAATTTTAACCGAACCGAAAAATGCGATTATCAAGCAATATCAAGCATTATTCCAAAT
GGAAGGTGTTGAGCTGAAATTTACCAAAGAGGCGTTAATTGCAATCGCGCAGAAATCTATTTCACGCAAAACCGGTGCAC
GCGGTTTACGCTCGATTGTTGAGAATCTACTGTTAGATACGATGTATAACTTGCCGACACTTAAAGCAGAGAAAAATGTG
AAAAAAGTGACGGTTGGCAAAGGTTGTGTTGAAAACGGCGATAAGCCGAAAGTAGAGTAA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(9-44)

AAA domain (Cdc48 subfamily) (AAA_2)

(116-314)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(321-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

54.964

98.568

0.542
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.186

92.601

0.52