Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACI3NC_RS26255 Genome accession   NZ_CP173570
Coordinates   5174191..5174847 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 98198     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5169191..5179847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI3NC_RS26225 (ACI3NC_26205) dcyD 5170071..5171057 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  ACI3NC_RS26230 (ACI3NC_26210) tcyL 5171072..5171740 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACI3NC_RS26235 (ACI3NC_26215) tcyN 5171737..5172489 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACI3NC_RS26240 (ACI3NC_26220) sdiA 5172719..5173441 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ACI3NC_RS26245 (ACI3NC_26225) yecF 5173508..5173732 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACI3NC_RS26250 (ACI3NC_26230) yecU 5173719..5173895 (-) 177 WP_000590347.1 protein YecU -
  ACI3NC_RS26255 (ACI3NC_26235) letA 5174191..5174847 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACI3NC_RS26260 (ACI3NC_26240) uvrC 5174844..5176676 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACI3NC_RS26265 (ACI3NC_26245) pgsA 5176733..5177281 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI3NC_RS26285 (ACI3NC_26265) yecA 5177931..5178596 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=961006 ACI3NC_RS26255 WP_000611328.1 5174191..5174847(+) (letA) [Escherichia coli strain 98198]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=961006 ACI3NC_RS26255 WP_000611328.1 5174191..5174847(+) (letA) [Escherichia coli strain 98198]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482