Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACI3M5_RS11455 Genome accession   NZ_CP173544
Coordinates   1794931..1795587 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 98206     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1789931..1800587
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI3M5_RS11425 (ACI3M5_11420) yecA 1791182..1791847 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  ACI3M5_RS11445 (ACI3M5_11440) pgsA 1792497..1793045 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI3M5_RS11450 (ACI3M5_11445) uvrC 1793102..1794934 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACI3M5_RS11455 (ACI3M5_11450) letA 1794931..1795587 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACI3M5_RS11460 (ACI3M5_11455) - 1795729..1795800 (+) 72 Protein_1752 transcriptional regulator -
  ACI3M5_RS11465 (ACI3M5_11460) yecU 1795883..1796059 (+) 177 WP_000590347.1 protein YecU -
  ACI3M5_RS11470 (ACI3M5_11465) yecF 1796046..1796270 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACI3M5_RS11475 (ACI3M5_11470) sdiA 1796337..1797059 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  ACI3M5_RS11480 (ACI3M5_11475) tcyN 1797289..1798041 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACI3M5_RS11485 (ACI3M5_11480) tcyL 1798038..1798706 (-) 669 WP_021548743.1 cystine ABC transporter permease -
  ACI3M5_RS11490 (ACI3M5_11485) dcyD 1798721..1799707 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=960441 ACI3M5_RS11455 WP_000611335.1 1794931..1795587(-) (letA) [Escherichia coli strain 98206]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=960441 ACI3M5_RS11455 WP_000611335.1 1794931..1795587(-) (letA) [Escherichia coli strain 98206]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486