Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACI3MW_RS01830 Genome accession   NZ_CP173528
Coordinates   220510..221166 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 98210     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 215510..226166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI3MW_RS01800 (ACI3MW_01800) dcyD 216390..217376 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  ACI3MW_RS01805 (ACI3MW_01805) tcyL 217391..218059 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACI3MW_RS01810 (ACI3MW_01810) tcyN 218056..218808 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACI3MW_RS01815 (ACI3MW_01815) sdiA 219038..219760 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ACI3MW_RS01820 (ACI3MW_01820) yecF 219827..220051 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACI3MW_RS01825 (ACI3MW_01825) yecU 220038..220214 (-) 177 WP_000590347.1 protein YecU -
  ACI3MW_RS01830 (ACI3MW_01830) letA 220510..221166 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACI3MW_RS01835 (ACI3MW_01835) uvrC 221163..222995 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACI3MW_RS01840 (ACI3MW_01840) pgsA 223052..223600 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACI3MW_RS01860 (ACI3MW_01860) yecA 224250..224915 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=960100 ACI3MW_RS01830 WP_000611328.1 220510..221166(+) (letA) [Escherichia coli strain 98210]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=960100 ACI3MW_RS01830 WP_000611328.1 220510..221166(+) (letA) [Escherichia coli strain 98210]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482